Second Symposium on Precision Image-Guided Small Animal RadioTherapy, Vancouver, Canada, August 11-13 2014 Program: Second Symposium on Precision Image-Guided Small Animal RadioTherapy, Aug 11-13, 2014 Sunday August 10 18-21 hr: Registration + Icebreaker reception Monday August 11 8.00-9.00 9.00-9.10 9.10-9.55 Registration Opening address: F Verhaegen, B Gill (Maastricht & Vancouver) KEYNOTE ADDRESS A van der Kogel - High precision small animal radiotherapy – historic perspective and new opportunities Tumor/normal tissue models. Chair: XXX 9.55-10.10 10.10-10.25 10.25-10.40 R Bütof - Establishment of orthotopic tumor models for small animal image guided radiotherapy S Krueger - Use of a small animal image-guided irradiator in the development of a rat model of radiation cystitis R Lieverse - A review of radiation effects in healthy lungs in preclinical models 10.40-11.10 Coffee break 11.10-11.40 INVITED: D Jaffray - XXX 11.40-11.55 G Price - Optical surface sensing for rapid, accurate & repeatable X-ray free animal irradiation set-up & monitoring 11.55-12.10 12.10-12.40 N Zarghami - Histological evaluation of targeting accuracy of 3D-printed immobilization device for mouse irradiation Discussion Session I- Moderator: XXX 12.40-13.50 Lunch Research technology. Chair: XXX 14.20-14.35 14.35-14.50 Precision radiotherapy. Chair: XXX INVITED: R Hill - Use of X-Rad 225Cx small animal irradiator/imager for fractionated radiation treatment of orthotopic models of cervix cancer M Dolera - Canine meningiomas: comparison of palliative therapy, surgery and VMAT stereotactic frameless radiosurgery L Court - Pre-clinical studies on the relationship between quantitative image features and tumor phenotype 14.50-15.05 P Granton - Longitudinal evaluation of radiation induced lung fibrosis in mice using a dedicated small animal micro-irradiator 15.05-15.35 Coffee break 15.35-15.50 R Hase (Faxitron) - 15.50-16.05 A Treverton (XSTRAHL) - XXX 16.05-16.20 16.20-16.35 16.35-17.05 19.00 W McLauglin (PXi) - XXX F Verhaegen (SmART-Solutions) – XXX [or others] Discussion Session II - Moderator: XXX Symposium Dinner 13.50-14.20 News from the manufacturers. Chair: XXX Advancements in Integrated Dose Control of a Fixed Cone Beam Biological Irradiator Tuesday August 12 9.00-9.30 9.30-9.45 9.45-10.00 10.00-10.15 Research Technology. Chair: XXX INVITED: J Wong - XXX A Rubinstein - Investigating magnetic field dose effects in mice: a Monte Carlo study G Delpon - Monte Carlo derived dose distributions for small animal radiotherapy: a Gate and EGS comparison 10.15-10.30 10.30-10.45 10.45-11.15 M Belley - Overview of an inorganic nano-crystalline scintillator based fiber optic detector for real-time, in-vivo, small animal therapy dosimetry M Jermoumi - Comprehensive Quality Assurance phantom for the Small Animal Radiation Research Platform J Stewart - High-Precision Irradiation Targeting with On-line Radiation Field Positioning Uncertainty Corrections Coffee break 11.15-11.45 11.45-12.00 Precision radiotherapy. Chair: XXX INVITED: J Lum - Radiation Medicine: Enhancing the immune-modulatory roles of radiation H Lee - Investigation into the abscopal effect in mouse models of breast cancer using image-guided small animal radiotherapy 12.00-12.15 12.15-12.30 12.30-13.00 13.00-14.10 G Borst - Genetically engineered mouse models and high precision fractionated radiotherapy to unravel irradiation escape and design novel treatment strategies L Dubois - Preclinical Assessment of Efficacy of Radiation Dose Redistribution Based on Intratumoral FDG-PET Uptake Discussion Session III – Moderator: XXX Lunch 14.10-14.25 14.25-14.40 Imaging. Chair: XXX M Bazalova-Carter - Investigation of microCT image quality for the SARRP, PXi, and Stanford conformal radiotherapy system J Salguero - Hounsfield unit robustness in small animal Cone Beam CT 14.40-14.55 14.55-15.10 R Weersink - Targeting accuracy tests of bioluminescence imaging integrated with cone-beam CT for image-guided small animal irradiation F Giordano - Image-guided radiotherapy of orthotopically implanted glioblastoma multiforme using a modified standard micro-CT 15.10-15.30 Coffee break New facilities. Chair XXX 15.30-16.00 INVITED: E Ford - An Image-Guided Precision Proton Radiation Platform (PPRP) Benchmarked with Radiobiological Experiments 16.00-16.20 T Yoshizumi - Small Animal Irradiator Physics Program at a Large Academic Medical Center 16.20-16.40 M Manca - A CERN for radio-oncology? Background, design and roadmap of a biomedical experimental facility for particle therapy and related research at CERN Discussion Session IV - Moderator: XXX Free evening 16.40-17.10 Wednesday August 13 Imaging&Dosimetry. Chair: XXX 9.00-9.30 9.30-9.45 9.45-10.00 INVITED: J Dorsey - Leveraging the Small Animal Radiation Research Platform (SARRP) to develop a new generation of theranostic radiomodifiers S Yahjahnejad - Accessing tumor response in orthotopic glioma model using a precision image-guided micro-irradiator L Malfassi - The use of Magnetic Resonance Spectroscopy (MRS) in differential diagnosis of canine brain disease 10.00-10.15 M Balvert - Automated beam-on-time optimization for small animal radiotherapy treatment planning 10.15-10.45 Coffee break 10.45-11.15 11.15-11.30 The final word. Chair: XXX INVITED: K Butterworth - Image guided small animal radiotherapy applications in translational radiobiology S van Hoof - Comparison of homogeneous MV and kV pre-clinical radiation treatments for rat flank tumors 11.30-11.45 F Verhaegen – The need for networking in small animal radiotherapy research 11.45-12.15 Discussion session V – Moderator: XXX 12.15-12.25 B Gill, F Verhaegen – Best Young Speaker Award & closing the Symposium Posters 1. M Belley. Real-time verification of planned dose during treatment on a small animal image guided radiation therapy treatment system using a nano-scintillator fiber optic detector 2. P Granton. PlastiMouse 3. M Dolera. Stereotactic Radiotherapy in Canine Adrenal Tumors: 12 Cases 4. M Dolera - Adaptive hypofractionated volumetric modulated arc stereotactic radiotherapy (AHSR-VMAT) in rabbit’s thymoma
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