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Juan R. Del Valle - CV
Juan R. Del Valle, Ph.D.
Curriculum Vitae
December 5, 2014
CURRENT POSITION
Assistant Professor
Chemical Biology & Molecular Medicine Program
H. Lee Moffitt Cancer Center & Research Institute
12902 Magnolia Drive, MRC 3East
Tampa, FL 33612
CURRENT ACADEMIC APPOINTMENTS
Affiliate Assistant Professor
Department of Chemistry
College of Arts and Sciences
University of South Florida
4202 E. Fowler Ave.
Tampa, FL 33620
EDUCATION
1999-2004
1995-1999
Tel:
Fax:
Email:
Web:
(813) 745-6142
(813) 745-6817
[email protected]
labpages.moffitt.org/delvallej
Assistant Professor
Department of Oncologic Sciences
College of Medicine
University of South Florida
12901 Bruce B. Downs Blvd.
Tampa, FL 33612
Ph.D. in Organic Chemistry; University of California at San Diego
B.A. in Chemistry; Carleton College
POSTGRADUATE TRAINING
2004-2006
Postdoctoral Fellowship in Bioorganic Chemistry, Université de Montréal
EMPLOYMENT AND ACADEMIC APPOINTMENTS
2009-present
Assistant Professor, Chemical Biology & Molecular Medicine Program
H. Lee Moffitt Cancer Center & Research Institute
2009-present
Affiliate Assistant Professor, Department of Chemistry,
University of South Florida
2006-2008
Assistant Professor, Department of Chemistry and Biochemistry,
New Mexico State University
2004-2006
Postdoctoral Fellow, Department of Chemistry,
Université de Montréal (PI: Stephen Hanessian)
1999-2004
Graduate Research Associate, Department of Chemistry and Biochemistry,
University of California at San Diego (PI: Murray Goodman)
1998
REU Fellow, Department of Pharmaceutical Chemistry,
University of Utah (PI: Bradley Anderson)
RESEARCH INTERESTS
Peptide mimicry; Medicinal chemistry; Inhibitors of protein-protein interactions; Constrained amino
acids; Structure-based drug design; Natural product synthesis
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Juan R. Del Valle - CV
PEER-REVIEWED PUBLICATIONS (underline denotes corresponding authorship)
28. Kang C, Ranatunga S, Sarnowski MP, Del Valle JR. Solid-phase
tetrahydropyridazinedione-constrained peptides. Org. Lett. (2014), 16, 5434.
synthesis
of
27. Kim YB, Kang CW, Ranatunga S, Yang H, Sebti SM, Del Valle JR. Imidazo[1,2-a]pyridine-based
peptidomimetics as inhibitors of Akt. Bioorg. Med. Chem. Lett. (2014) 24, 4650.
26. Ranatunga S, Tang CA, Kang C, Kloppenburg B, Kriss CL, Hu CA, Del Valle JR. Synthesis of
novel tricyclic chromenone-based inhibitors of IRE-1 RNase activity. J. Med. Chem. (2014) 57,
4289.
** Highlighted in SciBx ‘This Week in Therapeutics’ DOI: 10.1038/scibx.2014.702**
25. Tang, CA, Ranatunga S, Kriss, CL, Cubbitt CL, Pinilla-Ibarz JA, Del Valle JR, Hu CA. Inhibition of
ER stress-associated IRE-1/XBP-1 pathway reduces leukemic cell survival. J. Clin. Inv. (2014)
124, 2585.
** Highlighted in Cancer Discovery ‘Research Watch’ DOI: 10.1158/2159-8290.CD-RW2014-114**
** Highlighted in SciBx ‘This Week in Therapeutics’ DOI: 10.1038/scibx.2014.702**
24. Dorich S, Del Valle JR, Hanessian S. Synthesis of functionalized octahydroindoles related to
daphnyphyllum alkaloids. Synlett. (2014) 25, 799-804.
23. Kang C, Sun Y, Del Valle JR. Substituted
peptidomimetics. Org. Lett. (2012) 14, 6162-5.
imidazo[1,2-a]pyridines
as
beta-strand
22. Ranatunga S, Tang CA, Hu CA, Del Valle JR. Total synthesis and structural confirmation of
lucentamycin A. J. Org. Chem. (2012) 77, 9859-64.
21. Cha JW, Park JS, Sim T, N SJ, Kwon HC, Del Valle JR, Fenical W. Structure assignment of
lucentamycin E and revision of the olefin geometries of the marine-derived lucentamycins. J. Nat.
Prod. (2012) 75, 1648.
20. Kim YB, Balasis ME, Doi K, Berndt N, DuBoulay C, Hu CC, Guida W, Wang HG, Sebti SM, Del
Valle JR. Synthesis and evaluation of substituted hexahydronaphthalene derivatives as novel
inhibitors of the Mcl-1/BimBH3 interaction. Bioorg. Med. Chem. Lett. (2012) 22, 5961-5.
19. Kriss CL, Pinilla-Ibarz JA, Mallioux A, Powers JJ, Tang CA, Kang C, Zanesi N, Epling-Burnette
PK, Sotomayor EM, Croce CM, Del Valle JR, Hu, CA. Overexpression of TCL1 activates
endoplasmic reticulum stress response: A novel mechanism of leukemic progression in mice.
Blood (2012) 120, 1027-1038.
18. Ranatunga S, Kim JS, Pal U, Del Valle JR. An Ester Enolate-Claisen Rearrangement Route to
Substituted 4-Alkylideneprolines. Studies toward a Definitive Structural Revision of Lucentamycin
A. J. Org. Chem. (2011) 76, 8962-76.
** Selected for ACS ‘Virtual Issue on Peptide Chemistry’. http://pubs.acs.org/page/vi/2012/peptide.html**
17. Ranatunga S, Del Valle JR. Synthesis of GSK3b-Mimetic Inhibitors of Akt Featuring a Novel
Extended Dipeptide Surrogate. Bioorg. Med. Chem. Lett. (2011) 21, 7166-9.
16. Kim YB, Del Valle JR. Synthesis of a diversifiable cis-dehydrodecalin scaffold based on
meiogynin A. Tetrahedron Lett. (2011) 52, 6396-8.
15. Hanessian S, Vakiti RR, Dorich S, Banerjee S, Lecomte F, Del Valle JR, Zhang J, DeschenesSimard B. Total synthesis of pactamycin. Angew. Chem. Int .Ed. (2011) 50, 3497-500.
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Juan R. Del Valle - CV
14. Ranatunga S, Liyanage W, Del Valle JR. Synthesis and conformational analysis of bicyclic
extended dipeptide surrogates. J. Org. Chem. (2010) 75, 5113-25. PMCID: 2914495.
13. Ranatunga S, Del Valle JR. Synthesis of Boc-protected bicycloproline. Tetrahedron Lett. (2009)
50, 2464-6.
12. Pal U, Ranatunga S, Ariyarathna Y, Del Valle JR. Total synthesis of the putative structure of
lucentamycin A. Org. Lett. (2009) 11, 5298-301.
11. Hanessian S, Wang X, Ersmark K, Del Valle JR, Klegraf E. Total synthesis and structural
revision of the presumed aeruginosins 205A and B. Org. Lett. (2009) 11, 4232-5.
10. Liyanage W, Weerasinghe L, Strong RK, Del Valle JR. Synthesis of carbapyochelins via
diastereoselective azidation of 5-(ethoxycarbonyl)methylproline derivatives. J. Org. Chem. (2008)
73, 7420-3.
9. Ersmark K, Del Valle JR, Hanessian S. Chemistry and biology of the aeruginosin family of serine
protease inhibitors. Angew. Chem. Int. Ed. (2008) 47, 1202-23.
8. Hanessian S, Ersmark K, Wang X, Del Valle JR, Blomberg N, Xue Y. Structure-based organic
synthesis of unnatural aeruginosin hybrids as potent inhibitors of thrombin. Bioorg. Med. Chem.
Lett. (2007) 17, 3480-5.
7. Hanessian S, Del Valle JR, Xue Y, Blomberg, N. Total synthesis and structural confirmation of
chlorodysinosin A. J. Am. Chem. Soc. (2006) 128, 10491-5.
6. Zapf CW, Del Valle JR, Goodman M. Utilizing the intramolecular Fukuyama-Mitsunobu reaction
for a flexible synthesis of novel heterocyclic scaffolds for peptidomimetic drug design. Bioorg.
Med. Chem. Lett. (2005) 15, 4033-6.
5. Hanessian S, Tremblay M, Marzi M, Del Valle JR. Synthetic studies in the intramolecular
carbocyclization of N-acyloxyiminium ions. Stereoelectronic and steric implications of nucleophilic
alkene, alkyne, and allene tethers. J. Org. Chem. (2005) 70, 5070-85.
4. Del Valle JR, Goodman M. An efficient RCM-based synthesis of orthogonally protected mesoDAP and FK565. J. Org. Chem. (2004) 69, 8946-8.
3. Del Valle JR, Goodman M. Asymmetric hydrogenations for the synthesis of Boc-protected 4alkylprolinols and prolines. J. Org. Chem. (2003) 68, 3923-31.
2. Del Valle JR, Goodman M. Stereoselective synthesis of Boc-protected cis and trans-4trifluoromethylprolines by asymmetric hydrogenation reactions. Angew. Chem. Int. Ed. (2002) 41,
1600-2.
1. Goodman M, Del Valle JR, Amino Y, Benedetti E. Molecular basis of sweet taste in dipeptide
taste ligands. Pure Appl. Chem. (2002) 74, 1109-16.
PATENTS
Del Valle JR, Hu CA. Inhibitors of the IRE-1/XBP-1 pathway and methods of using thereof. PCT Int.
Appl. (2014) WO 2014176348.
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Juan R. Del Valle - CV
BOOK CHAPTERS AND CONFERENCE PROCEEDINGS
4. Del Valle JR, Thierren E, Hanessian S. Aeruginosins as thrombin inhibitors. In Natural Products
in Medicinal Chemistry, Vol. 60: Wiley-VCH; 2013. p. 333-56.
3. Ranatunga S, Kim JS, Del Valle JR. Synthetic studies toward lucentamycin A and 3-alkyl-4nd
alkylideneprolines via ester enolate-Claisen rearrangement. In Peptides: Proceedings of the 22
American Peptide Symposium (2011).
2. Del Valle JR, Wang X, Ersmark K, Hanessian S. Beta-substituted D-leucines and their relevance
in the total synthesis of natural and unnatural aeruginosins. In Asymmetric Synthesis and
Application of alpha-Amino Acids: American Chemical Society; 2009. p. 443-61.
1. Goodman M, Del Valle JR, Smith ND. Novel building blocks for peptidomimetic chemistry.
Biopolymers (2003) 71, 292.
SCIENTIFIC ABSTRACTS/POSTERS
21. Ranatunga S, Tang CA, Kang C, Kloppenburg B, Kriss CL, Hu CA, Del Valle JR. Novel tricyclic
chromenone-based inhibitors of IRE-1 RNase activity. Moffitt Scientific Symposium, Tampa, May
2014.
20. Kang C, Sun Y, Del Valle JR. IP-tides: Imidazo[1,2-a]pyridine-based peptidomimetics. American
Peptide Society Symposium, Waikaloa, June 2013.
19. Ranatunga S, Del Valle JR. Total synthesis and structural revision of lucentamycin A. American
Peptide Society Symposium, Waikaloa, June 2013.
18. Ranatunga S, Del Valle JR. Design and synthesis of novel macrocyclic beta-strand orthotics.
American Peptide Society Symposium, Waikaloa, June 2013.
17. Kim YB, Kang C, Yang, Sebti SM, Del Valle JR. Peptidomimetic inhibitors of Akt and SGK
targeting the substrate binding domain. American Peptide Society Symposium, Waikaloa, June
2013.
16. Kim YB, Kang C, Ranatunga S, Yang, Sebti SM, Del Valle JR. Design and synthesis of
substrate-mimetic Akt inhibitors based on the structure of GSK3beta. Moffitt Scientific
Symposium, Tampa, FL, May 2013.
15. Kim YB, Balasis ME, DuBoulay C, Wang HG, Sebti SM Guida W, Hu CA, Del Valle JR. Synthesis
of hexahydronaphthalene derivatives and their biological evaluation as Mcl-1 antagonists. Gordon
Research Conference Bioorganic Chemistry, Andover, NH, June 2012.
14. Kim YB, Balasis ME, DuBoulay C, Wang HG, Sebti SM Guida W, Hu CA, Del Valle JR. Synthesis
of hexahydronaphthalene derivatives and their biological evaluation as Mcl-1 antagonists. Moffitt
Scientific Symposium, Tampa, May 2012.
13. Ranatunga S, Del Valle JR. Synthesis of Novel Extended Dipeptide Surrogates and their
Incorporation into Peptidomimetic Inhibitors of Akt. National Meeting of the American Peptide
Society, San Diego, June 2011.
12. Ranatunga S, Kim JS, Del Valle JR. Synthetic Studies Toward Lucentamycin A and 3-Alkyl-4Alkylideneprolines via Ester Enolate-Claisen Rearrangement. National Meeting of the American
Peptide Society, San Diego, June 2011.
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Juan R. Del Valle - CV
11. Ranatunga S, Kim JS, Del Valle JR. Exploring an Ester Enolate-Claisen Rearrangement Route
to Lucentamycin A and Related 3-Alkyl-4-Alkylideneprolines. 87th ACS FAME Conference, Palm
Harbor, Florida, May 2011.
10. Ranatunga S, Kim JS, Del Valle JR. Exploring an Ester Enolate-Claisen Rearrangement Route
to Lucentamycin A and Related 3-Alkyl-4-Alkylideneprolines. 9th Annual Castle Conference,
Tampa, April 2011.
9. Ranatunga S, Pal U, Del Valle JR. Synthetic Studies Toward the Cytotoxic Marine Tripeptide
Lucentamycin A. National Meeting of the American Chemical, Boston, MA, August 2010
8. Ranatunga S, Yang H, Sebti S, Del Valle JR. Synthesis of Akt Inhibitors Using a Bicyclic Prolineth
Based Scaffold as the Peptidomimetic Core. 8 Annual Castle Conference, Tampa, FL, April
2010.
7. Ranatunga S, Yang H, Sebti S, Del Valle JR. Synthesis of Akt Inhibitors Using a Bicyclic ProlineBased Scaffold as the Peptidomimetic Core. Moffitt Symposium, Tampa, FL, March 2010.
6. Ranatunga S, Del Valle JR. Synthesis of Extended Dipeptide Surrogates for Akt Inhibitor Design.
FCoE-BITT Symposium on Drug Design, Discovery, and Delivery, Tampa, FL, October 2009.
5. Liyanage W, Del Valle JR. Reactions of α/β-Proline Enolates for the Synthesis of Constrained
Peptidomimetics. National Meeting of the American Peptide Society, Bloomington, June 2009.
4. Del Valle JR. Total Synthesis and Structural Confirmation of Chlorodysinosin A. Quebec-Ontario
Symposium of Bioorganic Chemistry, St. Adéle, November 2005.
3. Del Valle JR, Goodman M. Asymmetric Hydrogenations for the Synthesis of 4-Alkylprolines.
National Meeting of the American Peptide Society, Boston, April 2003.
2. Kwak J, Del Valle JR, Goodman M. Collagen Mimetics Incorporating Hydroxyproline and
Fluoroproline Guest Residues. National Meeting of the American Peptide Society, San Diego,
June 2001.
1. Del Valle JR, Goodman M. Synthesis of Novel Fluorinated Building Blocks for Peptidomimetic
Drug Design. National Meeting of the American Chemical Society, San Diego, April 2001.
RESEARCH SUPPORT
Active Grants
Targeting Akt with substrate-mimetic antagonists
Grant #:
5R21CA167215
PI:
Del Valle JR
Dates:
9/12 – 08/15
Source:
NIH/NCI
Effort:
20%
Role:
Principal Investigator
Direct Costs:
$239,250
Total Award:
$403,137
Targeting antigen-induced ER stress response in B-cell chronic lymphocytic leukemia
Grant #:
1R01CA163910-01A1
PI:
Hu, CA
Dates:
9/13 – 06/18
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Juan R. Del Valle - CV
Source:
Effort:
Role:
Direct Costs:
Total Award:
NIH/NCI
10%
Co-Investigator
$1,037,500
$1,748,188
Inhibition of the IRE-1/XBP-1 pathway in B-cell cancer
PI:
Del Valle, JR, Hu CA (MPI)
Source:
Moffitt Team Science (Internal)
Effort:
5%
Role:
Principal Investigator
Direct Costs:
$150,000
Total Requested: $150,000
Completed Grants
Chemical and biological studies of marine-derived non-ribosomal peptides
Grant #:
1BN03
PI:
Del Valle JR
Source:
Bankhead Coley Research Program (FL DOH)
Effort:
25%
Role:
Principal Investigator
Direct Costs:
$347,825
Total Award:
$400,000
Natural product-inspired approaches targeting Mcl-1
Grant #:
1KN03
PI:
Del Valle JR
Source:
James & Esther King Biomedical Research Program (FL DOH)
Effort:
25%
Role:
Principal Investigator
Direct Costs:
$347,825
Total Award:
$400,000
Synthetic methods toward antimicrobial tert-alkylamino carbocycles
Grant #:
SC2AI081526
PI:
Del Valle JR
Source:
NIH/NIAID
Effort:
50%
Role:
Principal Investigator
Direct Costs:
$200,00
Total Award:
$282,800
Synthesis of functional probes for siderocalin-induced apoptosis
Grant #:
IRG9309214
PI:
Pledger WJ
Source:
American Cancer Society
Effort:
10%
Role:
Project Leader
Direct Costs:
$30,000
Total Award:
$30,000
Probing novel mechanisms to target kinases for cancer drug discovery
Grant #:
n/a
PI:
Sebti SM
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Juan R. Del Valle - CV
Source:
Effort:
Role:
Direct Costs:
Total Award:
Anna Valentine Cancer Fund FIG (Internal)
1%
Project Leader
$75,000
$75,000
Synthesis of new ligands for the characterization of siderophore-ExFABP interactions
Grant #:
U54CA132383
PI:
O’Connell M
Source:
NIH/NCI
Effort:
33%
Role:
Project Leader
Direct Costs:
$245,066
Total Award:
$345,317
SEMINARS AND INVITED PRESENTATIONS
th
2015
249 American Chemical Society National Meeting, Denver, CO (2 invited talks)
2014
USF Health, Dept. of Molecular Medicine
2014
Canadian Society for Chemistry National Meeting, Vancouver, BC
2014
University of Denver, Dept. of Chemistry and Biochemistry
2014
University of New Mexico, Dept. of Chemistry and Chemical Biology
2014
University of Florida, Department of Medicinal Chemistry
2013
Florida Annual Meeting of the American Chemical Society, Palm Harbor, FL
2012
Southeastern Regional Meeting of the American Chemical Society, Raleigh, NC
2008
Fred Hutchinson Cancer Research Center, Division of Basic Science
2007
New Mexico Institute of Mining and Technology, Dept. of Chemistry
HONORS AND AWARDS
2010
CIBA Young Scientist Award, awarded by the CIBA Foundation and ACS YCC
2010
Milestone Award, awarded by the Miles for Moffitt Foundation
2004
Teddy Traylor Award for graduate research, awarded by the University of California
at San Diego
2004
Exemplary Teaching Assistant Performance Award, awarded by the University of
California at San Diego
2002
American Peptide Society Travel Award
1999-2001
San Diego Fellowship, awarded by the University of California at San Diego
1998
REU Fellowship, University of Utah
TEACHING EXPERIENCE
Courses Taught
2014
Lecturer: Bioethics (PCB 6932), Cancer Biology Program, MCC
2014-present Lecturer: Cancer Biology III (PCB 6205), Cancer Biology Program, MCC
2012-2013
Lecturer: Cancer Biology I (PCB 6230), Cancer Biology Program, MCC
2011-present Lecturer: Introduction to Medicinal Chemistry (CHEM 4932/6938), Department of
Chemistry and Biochemistry, USF
2009-present Lecturer: Drug Discovery Colloquium (CHEM 6936), Department of Chemistry and
Biochemistry, USF
2006-2009
Course Instructor: Organic Chemistry I (CHEM 313), Department of Chemistry and
Biochemistry, NMSU
2006-2009
Course Instructor: Advanced Organic Chemistry (CHEM 466/515), Department of
Chemistry and Biochemistry, NMSU
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Juan R. Del Valle - CV
Undergraduate Mentoring
2008-2009
MARC (Minority Access to Research Careers) Mentor for Leticia A. Montoya
2007
Undergraduate Research Mentor for Christian Talamantes
2006
Undergraduate Research Mentor for Lee Uranga
Graduate Mentoring
2014-present Ph.D. Graduate Student Advisor for Matthew Sarnowski (USF Chemistry)
2006-2012
Ph.D. Graduate Student Advisor for Sujeewa R. Mahanthe Mudiyanselage
2006-2009
M.S. Graduate Student Advisorfor Wathsala Liyanage
2006-2009
Graduate Research Advisor for Laksiri Weerasinghe
2007-2008
Graduate Research Advisor for Yamuna Ariyarathna
Postdoctoral Mentoring
2012-present Sujeewa Ranatunga, Ph.D.
2010-present Chang Won Kang, Ph.D.
2009-2013
Young B. Kim, Ph.D.
2010-2012
Yongmao Sun, Ph.D.
2009-2011
Jinsoo Kim, Ph.D.
2008-2009
Ujjwal Pal, Ph.D.
Student Advising
2014
2012
2012
2012
2009
2009
2008
2008
2008
2008
2007
2007
2007
2006
2006
Ph.D. Thesis Committee, Brent Kuenzi
Ph.D. Thesis Committee, Sujeewa Mudiyanselage, Chair
Ph.D. Thesis Committee, Hyun Joo Kil, Member
Ph.D. Thesis Committee, Courtney DeBoulay, Member
M.S. Thesis Committee, Wathsala Liyanage, Chair
Comprehensive Exam Committee, Sujeewa Mudiyanselage, Chair
Ph.D. Thesis Committee, Kris Waynant, Member
Comprehensive Exam Committee, Sarah Gibson, Member
M.S. Thesis Committee, Jon Shirley, Member
Comprehensive Exam Committee, Paul Wiget, Member
Comprehensive Exam Committee, Kris Waynant, Member
Comprehensive Exam Committee, Ritwik Burai, Member
Ph.D. Thesis Committee, Shaofeng Duan, Member
M.S. Thesis Committee, Jennifer Bell, Member
Ph.D. Thesis Committee, Jacob Strousse, Member
SERVICE
Professional Service
2014
NIH/NCI Ad Hoc Reviewer, DMP Study Section
2013-present Member, Nominating Committee, American Peptide Society
rd
2013
Session Chair, Peptidomimetics, 23 American Peptide Society Symposium
2013
NIH Early Career Reviewer, SBCB Study Section
2013
NIH/NCI Ad Hoc Reviewer, Developmental Cancer Therapeutics
2011-present Co-Chair, Student Affairs Committee, American Peptide Society
2006-present Reviewer of submitted manuscripts for the following publications:
Journal of the American Chemical Society, Journal of Organic Chemistry, Organic
Letters, Tetrahedron, Tetrahedron Letters, Chemical Communications, European
Journal of Medicinal Chemistry, Bioorganic Medicinal Chemistry, Bioorganic
Medicinal Chemistry Letters, PLoS One
2012
NIH/NCI Ad Hoc Reviewer, Anticancer Therapeutics Topic 255 SBIR Panel
2011
NIH/NCI Ad Hoc Reviewer, Anticancer Therapeutics Topic 255 SBIR Panel
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Juan R. Del Valle - CV
2008
NSF Ad Hoc Reviewer, CRIF-MU Special Emphasis Panel
Institutional Committees
2013-present Research Value Analysis Committee
2013-present Chemical Biology Advisory Committee
2011-2013
Institutional Product Evaluation Committee
2011-2013
Research Product Evaluation Committee
2012
ACS Internal Research Grant Review Committee
2012
OTMC Internship Program Review Committee
2009-2010
Investigator Webpage Committee
2006-2009
Stockroom Safety Committee
2006-2009
Chem Club Committee
Community Outreach
th
2014
Faculty Judge, 12 Annual Castle Conference, Tampa, FL
rd
2013
Travel Award Judge, 23 American Peptide Society Symposium, Waikaloa, HI
nd
2011
Faculty Judge, 22 American Peptide Society Symposium, San Diego, CA
nd
2011
Travel Award Judge, 22 American Peptide Society Symposium, San Diego, CA
th
2010
Faculty Judge, 8 Annual Castle Conference, Tampa, FL
2009
Faculty Judge, American Peptide Society Symposium, Bloomington, IN
2007
Volunteer, Regional Chemical Olympics Competition, Las Cruces, NM
2007
Faculty Judge, New Mexico Tech Senior Thesis Symposium, Socorro, NM
PROFESSIONAL ASSOCIATIONS
2009-present
American Association for Cancer Research, Member
2006-present
American Association for the Advancement of Science, Member
2001-present
American Peptide Society, Member
1999-present
American Chemical Society, Member
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