9. Kaklamani

Introduction and Welcome
Georgina Kaklamani
Foundation of Research and Technology- Hellas (FO.R.TH)
Institute of Electronic Structure and Laser (I.E.S.L)
[email protected]
Training School COST Action NAMABIO, 14–17 October 2014, Frederick University, Nicosia, Cyprus
Foundation of Research and Technology-Hellas (FO.R.TH)
 Institute of Electronic Structure and Laser
 Institute of Molecular Biology and Biotechnology
 Institute of Computer Science
 Institute of Applied and Computational Mathematics
 Institute of Mediterranean studies
 Institute of Chemical Engineering Sciences
 Biomedical Research Institute
Institute of Electronic Structure and Laser (I.E.S.L)
• Laser Interactions and Photonics Division
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Strong Field Physics
Atoms, Molecules and Clusters
Theoretical Atomic, Molecular and Optical Physics
Photon Science Applications
• Biophotonics
• Laser processing of materials
• Diagnostic methods and instrumentation
• Lasers and Cultural Heritage
• Materials and Devices Division
• Micro/Nano-electronics
• Soft Matter
• Polymer & Colloid Science
• Hybrid Nanostructures
• Magnetic Materials
• Theoretical Condensed Matter Physics
• Photonic, Phononic and Meta-materials
• Astrophysics and Astronomy (Skinakas Observatory)
Hybrid Nanostructures Group - Personnel
Name
Title
Affiliation
Degree
S. H. Anastasiadis
Professor
Univ. of Crete
Dept. of Chemistry
Ph.D. 1988
Princeton Univ.
M. Vamvakaki
Associate
Professor
Univ. of Crete
Dept. of Materials Sci.
Ph.D. 1998
University of Sussex
I. A. Bitsanis
Principal
Researcher
FO.R.T.H.-I.E.S.L.
Ph.D. 1988
Univ. of Minnesota
K. Chrissopoulou
Researcher
FO.R.T.H.-I.E.S.L.
Ph.D. 2000
University of Patras
L. Papoutsakis
Lab.
Technician
FO.R.T.H.-I.E.S.L.
M.Sc. 2002
University of Crete
Hybrid Nanostructures Group - Personnel
Name
Title
Affiliation
Degree
M. Kaliva
Postdoctoral
Fellow
FO.R.T.H.-I.E.S.L.
Ph.D. 2004
University of Crete
A. Rissanou
Postdoctoral
Fellow
FO.R.T.H.-I.E.S.L.
Ph.D. 2003
University of Crete
G. Kaklamani
Postdoctoral
Fellow
FO.R.T.H.-I.E.S.L.
Ph.D. 2012
Univ. of Birmingham
K. Vasilopoulos
Postdoctoral
Fellow
FO.R.T.H.-I.E.S.L.
Ph.D. 2009
Univ. of Thessaloniki
M. E. Kalyva
Postdoctoral
Fellow
FO.R.T.H.-I.E.S.L.
Ph.D. 2008
Univ. of Patras
Hybrid Nanostructures Group – Research Activities
Research Areas
Keywords
Polymer Surfaces, Interfaces, Thin Films &
Anchored Chains
Structure, self-assembly, relaxation
Synthesis of Functional Polymer Materials
Amphiphiles, polyampholytes, (micro)gels,
polymer brushes
“Smart” Materials: responsive to pH,
temperature, humidity, …
Surface restructuring, (micro)gel swelling,
micellization
Polymer Nanohybrids
Nanocatalysts, nano-objects, polymer
nanocomposites
Multiconstituent Systems (block
copolymers, polymer blends)
Morphology, phase transitions, dynamicsdiffusion, rheology, compatibilization
Multiscale Computer Simulations
Coil-to-globule transition, adsorbed chains,
brushes
My Background
Degree/Title
Affiliation
B.Sc
Materials Science and Technology, Physical Sciences, University of Crete, Greece
M.Res
School of Metallurgy and Materials, College of Engineering and Physical Sciences,
University of Birmingham, UK
Ph.D.
School of Metallurgy and Materials, College of Engineering and Physical Sciences,
University of Birmingham, UK (EPSRC Scholarship)
Postdoctoral
Fellow
Department of Biochemical Engineering, School of Chemical Engineering, College
of Engineering and Physical Sciences, University of Birmingham, UK
Postdoctoral
Fellow
Nano Engineering and System Integration
LAAS-CNRS, Toulouse, France
Postdoctoral
Fellow
Foundation of Research and Technology –Hellas (FO.R.TH)
Institute of Electronic Structure and Laser (I.E.S.L)
Research Projects
 Effect of Active Screen Plasma Nitriding on the Cellular Compatibility of Polymeric
Biomaterials
 Nano-resolved Multi-scale Investigation of Human Tactile Sensations and Tissue
Engineered Biosensors (NanoBioTouch – FP7)
 Nanofluidics for Single Cell Manipulation (One_Chip)
 Smart Multi-functional Polymer Surfaces (Smart_Surf)
Research Projects
 Effect of Active Screen Plasma Nitriding on the Cellular Compatibility of Polymeric
Biomaterials
 Nano-resolved Multi-scale Investigation of Human Tactile Sensations and Tissue
Engineered Biosensors (NanoBioTouch – FP7)
 Nanofluidics for Single Cell Manipulation (One_Chip)
 Smart Multi-functional Polymer Surfaces (Smart_Surf)
Gas in
Effect of Active Screen Plasma Nitriding on the Cellular
Compatibility of Polymeric Biomaterials
fan
gas distributor
furnace wall
anode
UHMWPE
IONOMER GLASSES
3T3 Fibroblasts
Day 1
metal screen
cathode
Day 0-Day 7
Gas out
Day 14
Kaklamani et al.Applied Surface Science 273 (2013) 787– 798
Kaklamani et al. Materials Letters 111(2013)225–229
Kaklamani et al.Biomedical Materials. 5 (2010) 054102 (10pp)
Day 28
Research Projects
 Effect of Active Screen Plasma Nitriding on the Cellular Compatibility of Polymeric
Biomaterials
 Nano-resolved Multi-scale Investigation of Human Tactile Sensations and Tissue
Engineered Biosensors (NanoBioTouch – FP7)
 Nanofluidics for Single Cell Manipulation (One_Chip)
 Smart Multi-functional Polymer Surfaces (Smart_Surf)
Nano-resolved Multi-scale Investigation of Human Tactile Sensations
and Tissue Engineered Biosensors (NanoBioTouch – FP7)
To interface biological systems of ever
increasing complexity with silicon based
chips in order to produce a technology
capable of sensing mechanical and
temperature stimuli
Nano-resolved Multi-scale Investigation of Human Tactile Sensations
and Tissue Engineered Biosensors (NanoBioTouch – FP7)
2D Culture silicon
Substrate
Kaklamani et al. Journal of Electrical Bioimpedance vol. 5 (2014) 55–73
Kaklamani et al. Journal of the Mechanical Behaviour of Biomedical Materials 36 (2014)
135–142
3D culture in a
hydrogel
Research Projects
 Effect of Active Screen Plasma Nitriding on the Cellular Compatibility of Polymeric
Biomaterials
 Nano-resolved Multi-scale Investigation of Human Tactile Sensations and Tissue
Engineered Biosensors (NanoBioTouch – FP7)
 Nanofluidics for Single Cell Manipulation (One_Chip)
 Smart Multi-functional Polymer Surfaces (Smart_Surf)
Nanofluidics for Single Cell Manipulation (One_Chip)
“Agarose as a Vehicle for Genomic Analysis” G.Kaklamani. A. Bancaud (under submission)
Research Projects
 Effect of Active Screen Plasma Nitriding on the Cellular Compatibility of Polymeric
Biomaterials
 Nano-resolved Multi-scale Investigation of Human Tactile Sensations and Tissue
Engineered Biosensors (NanoBioTouch – FP7)
 Nanofluidics for Single Cell Manipulation (One_Chip)
 Smart Multi-functional Polymer Surfaces (Smart_Surf)
Smart Multi-functional Polymer Surfaces (Smart_Surf)
Biomimetic materials / novel multifunctional surfaces
Design
Characterize
Optimize
wetting behavior alteration:
1. pH
2. Temperature
3. Solvent quality
4. Light illumination
Polymer brush “grafted from”
the microstructured Si surface
Scientific Interests
 Surface modification of Biomaterials
 Hydrogels as matrices for cell encapsulation-regenerative medicine
 Biosensing
 Microfluidics for biomedical applications-diagnostics
 Skin/bone implants
Thank You!!!

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