Referenten Veranstaltungsort Priv.-Doz. Dr. Francis Ayuketang Ayuk | UKE Klinik für Stammzelltransplantation Universitätsklinikum Hamburg-Eppendorf Martinistraße 52 20246 Hamburg Ian Karan Lecture Hall (N55) – Campus UKE Dr. Olaf Boenisch | UKE Klinik für Intensivmedizin Ian Karan Lecture Hall (N55) N67 N65 Campus Lehre N69 Prof. Dr. Jun Oh | UKE Klinik und Poliklinik für Kinder- und Jugendmedizin N7 1 N70 N73 Prof. Dr. Nicolaus Kroeger | UKE Direktor der Klinik für Stammzelltransplantation HPI N81 N55 N45 N46 N44 N43 Prof. Dr. Thomas Renné | UKE Direktor des Instituts für Klinische Chemie Kinder N23 N21 N27 O64 O70 W29 W31 REHA Prof. Dr. Friedrich Thaiss | UKE III. Medizinische Klinik und Poliklinik W40 Löwenstraße W34 O13 H H O55 O49 O38 O28 O28 O11 W32 Hotel OO2244 O57 O53 O44 W33 P O43 W35 O36 W37 O10 O58 O50 O26 O26 O33 W30 O22 O25 W12 Gesundheitszentrum Spectrum Dr. Manuela Tavares de Sousa | UKE Klinik und Poliklinik für Geburtshilfe und Pränatalmedizin O61 W14 Neues Klinikum N30 Campus Forschung N34 W27 N19 N17 W16 N26 O 46 O 48 O45 Baustelle Fortbildungsveranstaltung LVII Frickestraße N60 W23 N24 N22 N13 O59 fel d N36 ten O56 Bu N61 O54 N 80 N62 Prof. Dr. Giuseppe Remuzzi | Bergamo Hospital Director Department of Immunology and Clinical Transplantation and Director Department of Medicine Jacqueline Triankowski | UKE Klinik für Hepatobiliäre Chirurgie und Transplantationschirurgie Studienambulanz Transplantations-Centrum Transplantations-Akademie aHUS – clinical challenges The interdisciplinary approach Dienstag, 14. Febuar 2017 I 17.00 Uhr O35 Martinistraße Hauptzufahrt Curschmannstraße Universitätsklinikum Hamburg-Eppendorf Prof. Dr. Ulrich Wenzel | UKE III. Medizinische Klinik und Poliklinik In Kooperation mit Wir danken Alexion für die freundliche Unterstützung. Dear colleagues, friends and guests: Hemolytic uremic syndrome (HUS) is a thrombotic microangiopathy defined by thrombocytopenia, nonimmune microangiopathic hemolytic anemia and acute renal failure. The designation of atypical HUS (aHUS) is used to refer to those cases in which an infection by Shiga-like toxin-producing could be excluded with a poor outcome. About 60% of patients with aHUS have dysregulation of the alternative complement pathway. The kidney is the main target organ, but other organs are also affected and therefore most of the patients with aHUS need to be treated in an interdisciplinary approach. Studies performed in the last two decades have documented that hyperactivation of the complement system is the pathogenetic effector mechanism leading to the endothelial damage and the microvascular thrombosis in aHUS. Early diagnosis and identification of underlying pathogenetic mechanism allow specific support measures and therapies. In clinical trials in patients with aHUS, complement inhibition by eculizumab administration leads to a rapid and sustained normalization of hematological parameters with improvement in long-term outcome. To better understand new pathogenetic mechanisms of aHUS and learn more about recent therapeutic opportunities to treat this disease in the interdisciplinary approach we are proud to welcome Prof. Remuzzi, one of the best known and leading clinical scientist in this field, for this conference to discuss with him recent clinical cases presenting at our hospital. We are looking forward to welcome you for this conference. Yours teams of the University Transplant Center at the UKE Dienstag, 14. Februar 2017 17.00 Uhr aHUS – clinical challenges The interdisciplinary approach Chair: Prof. Dr. Jun Oh | UKE 5:00 – 5:15 p.m. Introduction Prof. Dr. Nicolaus Kroeger | UKE INVITED LECTURE: 5:15 – 6:00 p.m. Atypical hemolytic uremic syndrome – a systemic disease and multidisciplinary approach Prof. Dr. Giuseppe Remuzzi | Bergamo 7:00 – 7:10 p.m. aHUS Registry at the UKE Prof. Dr. Friedrich Thaiss | UKE Jacqueline Triankowski, Registry Coordinator | UKE 7:10 – 7:30 p.m. General Discussion – All Prof. Dr. Thomas Renné | UKE 7:30 – 7:40 p.m. Closing Remarks Prof. Dr. Jun Oh | UKE Refreshment CASE PRESENTATION AND DISCUSSION: 6:00 – 6:15 p.m. aHUS after bone marrow transplantation Priv.-Doz. Dr. Francis Ayuketang Ayuk | UKE 6:15 – 6:30 p.m. aHUS and intensive care unit Dr. Olaf Boenisch | UKE 6:30 – 6:45 p.m. aHUS and pregnancy Dr. Manuela Tavares de Sousa | UKE 6:45 – 7:00 p.m. aHUS and kidney transplantation Prof. Dr. Ulrich Wenzel | UKE Organisation Wissenschaftliche Organisation: Prof. Dr. Friedrich Thaiss E-Mail: [email protected] Veranstaltungsorganisation: Robert Kütemeier Telefon 040 7410 - 54777 Die Fortbildung wurde mit 3 Punkten bei der Ärztekammer Hamburg beantragt.
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