The 7th Congress of the Federation
of the Israel Societies for Experimental Biology
February 10-13, 2014 ● Eilat
SCIENTIFIC PROGRAM
ORAL PRESENTATIONS
(updated January 21)
1
Monday, February 10, 2014
15:30-16:00
Opening Ceremony
Opening Remarks:
Hall A - Herods Boutique
Yinon Ben-Neriah, Congress President
Yosef Yarden, FISEB President
Michael Sela, FISEB Founder
16:00-17:00
Plenary 1
Chairperson: Ada E. Yonath (Weizmann Institute of Science)
Hall A - Herods Boutique
This session is sponsored by the I-CORE Gene Regulation in Complex Human Disease
16:00
MULTISCALE MODELING OF COMPLEX BIOLOGICAL SYSTEMS AND PROCESSES
Arieh Warshel, University of Southern California, CA, USA
17:00-17:30
Coffee Break and Exhibition
17:30-20:00
PARALLEL SESSIONS A1, A6, C3, B4, D3, E1, E6, B2, G4
17:30-20:00
Parallel Session A1:
Principles of gene network evolution
Hall A - Herods Boutique
Chairpersons: Uri Alon (Weizmann Institute of Science) and Avigdor Eldar (Tel Aviv University)
17:30
EVOLUTIONARY TRADEOFFS AND THE GEOMETRY OF GENE EXPRESSION SPACE
Uri Alon, Weizmann Institute of Science
17:55
TRANSFER OF NON-CODING DNA DRIVES REGULATORY REWIRING IN BACTERIA
Tal Pupko, Tel Aviv University
18:20
CONFLICT RESOLUTION IN BACTERIAL POPULATIONS: THE ROLE OF BACTERIOCINS
Osnat Gillor, Ben-Gurion University of the Negev
18:45
METAZOAN OPERONS ACCELERATE RECOVERY FROM GROWTH ARRESTED STATES
Alon Zaslaver, The Hebrew University of Jerusalem
19:10
SOCIAL EVOLUTION UNDERLIES THE CO-EXISTENCE OF QUORUM-SENSING SYSTEMS IN
SYNTHETICALLY ENGINEERED AND NATURAL COMMUNITIES
Avigdor Eldar, Tel Aviv University
19:35
EVIDENCE FOR DETERMINISTIC VARIABILITY OF THE MAMMALIAN CELL CYCLE
DURATION
Sivan Pearl, The Hebrew University-Hadassah Medical School
2
Monday, February 10, 2014
17:30-20:00
Parallel Session A6:
Cellular responses to DNA damage
Hall B - Herods Boutique
Chairpersons: Michal Goldberg (The Hebrew University of Jerusalem) and Zvi Livneh (Weizmann Institute of
Science)
17:30
THE OTHER FACES OF THE PIM-2 ONCOGENE: CELL CYCLE ARREST, ACTIVATION OF
APOPTOSIS AND INVOLVEMENT IN THE DNA DAMAGE RESPONSE
Jeremyahu Don, Bar-Ilan University
17:55
APOBEC3 PROTEINS ARE INNATE ANTIVIRAL RESTRICTION FACTORS INVOLVED IN
CELLULAR GENOMIC DNA EDITING, MUTAGENESIS AND DSB REPAIR
Moshe Kotler, The Hebrew University-Hadassah Medical School
18:20
ROLE OF NUCLEAR ARCHITECTURE IN TOLERANCE OF DNA DAMAGE BY TRANSLESION
DNA SYNTHESIS
Zvi Livneh, Weizmann Institute of Science
18:45
DNA2 IS INVOLVED IN THE ETHIOLOGY OF ESTROGEN-DEPENDENT CANCERS
Michal Goldberg, The Hebrew University of Jerusalem
19:10
MECHANISMS OF TELOMERE LENGTH MAINTENANCE
Martin Kupiec, Tel Aviv University
19:35
WHY CROWDED CELLS ARE RESISTANT TO DNA DAMAGE
Nina Reuven, Weizmann Institute of Science
17:30-20:00
Parallel Session C3:
Ecology and evolution of stress
Hall C - Herods Boutique
Chairpersons: Lilach Hadany (Tel Aviv University) and Ariel Novoplansky (Ben-Gurion University of the
Negev)
17:30
ECOLOGY AND BIOGEOGRAPHY OF THE MICROBIAL POPULATIONS INHABITING A
GLOBALLY DISTRIBUTED DESERT PLANT
Shimshon Belkin, The Hebrew University of Jerusalem
17:55
ON THE ROLE OF STRESS IN EVOLUTION
Lilach Hadany, Tel Aviv University
18:20
THE EFFECT OF BACTERIA-PLANT COMMUNICATION PATHWAYS ON THE INTEGRITY OF
PLANT-ASSOCIATED BIOFILMS
Yaara Oppenheimer-Shaanan, Weizmann Institute of Science
18:45
EVOLUTIONARY DYNAMICS OF COOPERATIVE PROTEIN SECRETION IN MICROORGANISM
POPULATIONS
Naama Brenner, Technion-Israel Institute of Technology
19:10
TWO BACTERIAL PROGRAMMED CELL DEATH SYSTEMS: A MODEL FOR HOW TO
MAINTAIN AN ALTRUISTIC TRAIT
Hanna Engelberg-Kulka, The Hebrew University-Hadassah Medical School
19:35
ECOLOGICAL IMPLICATIONS OF ROOT-ROOT COMMUNICATION
Ariel Novoplansky, Ben-Gurion University of the Negev
3
Monday, February 10, 2014
17:30-20:00
Parallel Session B4:
Signaling pathways and networks
Chairpersons: Ido Amit (Weizmann Institute of Science) and Yoav I. Henis (Tel Aviv University)
Hall D - Dan
17:30
OLIGOMERIZATION AND SIGNALING BY TGF-β AND BMP RECEPTORS
Yoav I. Henis, Tel Aviv University
17:55
SIGNALLING BETWEEN ORGANELLES - UNCOVERING NEW CONTACT SITES
Maya Schuldiner, Weizmann Institute of Science
18:20
THE NUCLEAR TRANSLOCATION OF MAPKS: A NOVEL TARGET FOR THE CURE OF
SIGNALING-RELATED DISEASES
Rony Seger, Weizmann Institute of Science
18:45
Ab INITIO CHARACTERIZATION OF THE IMMUNE SYSTEM USING MASSIVELY PARALLEL
SINGLE CELL RNA-Seq
Ido Amit, Weizmann Institute of Science
19:10
TARGETING THE IMMUNE SYSTEM TO SEEK AND DESTROY TUMORS
Maya Zigler, The Hebrew University of Jerusalem
19:35
FOLLOWING SIGNAL PROPAGATION FROM THE CYTOPLASM TO THE β-ACTIN GENE IN
SINGLE LIVING CELLS
Yaron Shav-Tal, Bar-Ilan University
17:30-20:00
Parallel Session D3:
Innate immune response and inflammation
Hall E - Dan
Chairpersons: Ofer Mandelboim (The Hebrew University of Jerusalem) and Ariel Munitz (Tel Aviv University)
17:30
THE MOLECULAR SIGNALING MECHANISMS THAT TUNE NATURAL KILLER CELL
ACTIVATION THRESHOLD
Mira Barda-Saad, Bar-Ilan University
17:55
URINARY PATHOGENIC E. COLI KILL NATURAL KILLER CELLS TO ESTABLISH URINARY
TRACT INFECTION
Ofer Mandelboim, The Hebrew University of Jerusalem
18:20
CROSS TALK BETWEEN THE INNATE AND ADAPTIVE IMMUNE SYSTEMS UNDER CHRONIC
INFLAMMATORY CONDITIONS: CLINICAL IMPLICATIONS
Michal Baniyash, The Hebrew University of Jerusalem
18:45
A HOMEOSTATIC IL-13 RECEPTOR ALPHA 1:TREFOIL FACTOR 2 AXIS IN PULMONARY
FIBROSIS
Ariel Munitz, Tel Aviv University
19:10
WE ARE NOT ALONE: A MEETING WITH YOUR GUT MICROBIOME
Omry Koren, Bar-Ilan University
19:35
DECODING HUMAN CYTOMEGALOVIRUS
Noam Stern-Ginossar, Weizmann Institute of Science
4
Monday, February 10, 2014
17:30-20:00
Parallel Session E1:
Tissue engineering: building new tissues
Hall F - Dan
Chairpersons: Tal Dvir (Tel Aviv University) and Yaakov Nahmias (The Hebrew University of Jerusalem)
17:30
METABOLICALLY FUNCTIONAL, POLARIZED CULTURES OF PROLIFERATING HUMAN
HEPATOCYTES
Yaakov Nahmias, The Hebrew University of Jerusalem
17:55
GELS FOR CELLS: HYDROGEL SCAFFOLDS FOR TISSUE REGENERATION AND
BIOTECHNOLOGY
Dror Seliktar, Technion-Israel Institute of Technology
18:20
HOW DEEPLY CELLS FEEL: NUCLEUS-TO-CYTOSKELEON REGULATION BY MATRIXINDUCED TENSION AND PHOSPHORYLATION
Amnon Buxboim, The Hebrew University of Jerusalem and The University of Pennsylvania, PA, USA
18:45
ADVANCED TECHNOLOGIES FOR ENGINEERING CARDIAC TISSUES
Tal Dvir, Tel Aviv University
19:10
BIO-INSPIRED ALGINATE BIOMATERIAL FOR PROMOTING REGENERATION OF THE
OSTEOCHONDRAL INTERFACE
Emil Ruvinov, Ben-Gurion University of the Negev
19:35
CONTRACTILE FORCES REGULATE CELL DIVISION IN THREE-DIMENSIONAL
ENVIRONMENTS
Ayelet Lesman, California Institute of Technology, CA, USA
17:30-20:00
Parallel Session E6:
Mechanisms underlying neuronal plasticity
Hall H - Royal Beach
Chairpersons: Yadin Dudai (Weizmann Institute of Science) and Inna Slutsky (Tel Aviv University)
17:30
SYNAPTIC TENACITY: WHEN EVERYTHING CHANGES, DO THINGS REALLY STAY THE
SAME?
Noam Ziv, Technion-Israel Institute of Technology
17:55
MOLECULAR MECHANISMS OF MEMORY CONSOLIDATION IN THE CORTEX
Kobi Rosenblum, University of Haifa
18:20
HIPPOCAMPAL PLASTICITY: FROM SYNAPTIC DYNAMICS TO ALZHEIMER'S DISEASE
Inna Slutsky, Tel Aviv University
18:45
NEUROPLASTICITY IN THE VENTRAL PALLIDUM CONTRIBUTES TO COCAINE ADDICTION
Yonatan Kupchik, Medical University of South Carolina, SC, USA
19:10
LONG-TERM DYNAMICS OF CA1 HIPPOCAMPAL PLACE CODES
Yaniv Ziv, Stanford University, CA, USA and Weizmann Institute of Science
19:35
THE FIRST SECONDS OF HUMAN EPISODIC MEMORY
Yadin Dudai, Weizmann Institute of Science
5
Monday, February 10, 2014
17:30-20:00
Parallel Session B2:
Proteomic and structure-function of macromolecule assemblies
Hall I - Royal Beach
Chairpersons: Tamar Geiger (Tel Aviv University) and Irit Sagi (Weizmann Institute of Science)
17:30
ANTI-VIRAL AGENTS: MECHANISM OF ACTION AND VIRAL RESISTANCE
Isaiah Arkin, The Hebrew University of Jerusalem
17:55
STRUCTURE OF A FLEXIBLE CAPSID FOR GENE TRANSFER BY AGROBACTERIUM
TUMEFACIENS
Michael Elbaum, Weizmann Institute of Science
18:20
SOLVING DIFFICULT STRUCTURES OF MACROMOLECULAR ASSEMBLIES BY
COMBINATORIAL MODELING, CROSS-LINKING, AND MASS-SPECTROMETRY
Nir Kalisman, Stanford University School of Medicine, CA, USA
18:45
THE PRODUCTION PIPELINE OF THE MHC PEPTIDOME
Arie Admon, Technion-Israel Institute of Technology
19:10
LARGE SCALE BREAST CANCER CLINICAL PROTEOMICS USING HIGH-RESOLUTION MASS
SPECTROMETRY AND SUPER-SILAC
Tamar Geiger, Tel Aviv University
19:35
TARGETING MOLECULAR SELF-ASSEMBLY AS A NOVEL ANTI-VIRAL THERAPEUTIC
STRATEGY
Ayala Lampel, Tel Aviv University
17:30-20:00
Parallel Session G4:
Diabetes and common metabolic diseases
Hall J - Royal Beach
Chairpersons: Yuval Dor (The Hebrew University of Jerusalem) and Assaf Rudich (Ben-Gurion University of
the Negev)
17:30
PROGRAMMED SENESCENCE CONTRIBUTES TO BETA CELL GROWTH AND FUNCTION
Asaf Hellman, The Hebrew University-Hadassah Medical School
17:55
UREA CYCLE ENZYMES' MOONLIGHTING ROLE IN SYSTEMIC DISEASES
Ayelet Erez, Weizmann Institute of Science
18:20
GSK-3: FROM METABOLIC REGULATION TO CANCER AND NEURODEGENERATION
Hagit Eldar-Finkelman, Tel Aviv University
18:45
STIMULATION OF AUTOPHAGY IMPROVES ER STRESS-INDUCED DIABETES
Gil Leibowitz, Hadassah Hebrew University Hospital
19:10
LIVING HEALTHILY EVER AFTER- HOW SIRT6 PROMOTES HEALTHY LIFESPAN
Haim Y. Cohen, Bar-Ilan University
19:35
CANCER METABOLISM: MORE THAN JUST PROLIFERATION
Yoav Shaul, Koch Institute for Integrative Cancer Research, Whitehead Institute for Biomedical
Science, MA, USA
20:00
Welcome Reception with a performance by
Elisha Banay & The Forty Thieves
Pool Area - Dan
6
Tuesday, February 11, 2014
07:00-07:30
Coffee and Cakes
Halls D, E, F - Dan
07:30-08:45
PARALLEL EARLY BIRDS: HI, HII, HIII
07:30-08:45
Early bird HI:
Emerging high-bandwidth technologies in biomedical research
Hall D - Dan
Chairpersons: Yuval Dor (The Hebrew University of Jerusalem) and Shai Shen-Orr (Technion-Israel Institute
of Technology)
07:30
FROM FOCUSED PANELS TO WHOLE-GENOME APPROACHES: TAILORED SOLUTIONS
USING DEEP SEQUENCING
Florian Graedler, illumina GmbH, Germany
07:50
MASSIVELY INFORMATIVE: FUNDAMENTALS AND APPLICATIONS OF MASS CYTOMETRY
Mickael Meyrand, DVS Sciences, Europe
08:10
EMPOWER THE TRANSLATION OF NGS DISCOVERIES, TO THE APPLICATION OF
LABORATORY DEVELOPED TESTS
James White, NanoString Technologies, Europe
08:30
THE NANCY AND STEVEN GRAND INCPM: AN INTEGRATED-OMICS APPROACH TO BASIC
AND CLINICAL RESEARCH
Berta Strulovici, Weizmann Institute of Science
07:30-08:45
Early bird HII:
Should biology be taught in high school (IN HEBREW)
Hall E - Dan
Chairpersons: Anat Yarden (Weizmann Institute of Science) and Michal Zion (Bar-Ilan University)
07:30
SHOULD BIOLOGY BE TAUGHT IN HIGH SCHOOL? IMPLICATIONS FOR HIGHER
EDUCATION AND THE ISRAELI SOCIETY
Anat Yarden, Weizmann Institute of Science and Michal Zion, Bar-Ilan University
The panel will include the following experts:
Doron Ginsberg, Bar-Ilan University
Ruthy Mendelovici, Inspector General of Biology Teaching, Ministry of Education
Zemira Mevarech, Bar-Ilan University
Shulamit Michaeli, Bar-Ilan University
Anat Yarden, Weizmann Institute of Science
Michal Zion, Bar-Ilan University
Ehud Ziv, The Hebrew University of Jerusalem
07:30-08:45
Early bird HIII:
Life after grad school
Hall F - Dan
Chairpersons: Maya Schuldiner (Weizmann Institute of Science) and Noam Shomron (Tel Aviv University)
07:30
TO BE OR NOT TO BE.... (A POSTDOC)
Maya Schuldiner, Weizmann Institute of Science
08:00
BIOABROAD: A NETWORK OF ISRAELI ACADEMICS ABROAD
Noam Shomron, Tel Aviv University
08:30
General discussion
09:00-10:00
Plenary 2
Chairperson: Yosef Yarden (Weizmann Institute of Science)
09:00
GENOMIC APPROACHES TO CANCER
Todd R. Golub, Broad Institute of Harvard and MIT, MA, USA
10:00-10:30
Coffee Break and Exhibition
7
Hall A - Herods Boutique
Tuesday, February 11, 2014
10:30-13:00
PARALLEL SESSIONS: F1, B5, C4, F5, D4, D1, A2, F6, G5
10:30-13:00
Parallel Session F1:
Stem cells: from pluripotency to differentiation
Hall A - Herods Boutique
Chairpersons: Nissim Benvenisty (The Hebrew University of Jerusalem) and Jacob H. Hanna (Weizmann
Institute of Science)
10:30
THE TUMORIGENICITY OF HUMAN PLURIPOTENT STEM CELLS
Nissim Benvenisty, The Hebrew University of Jerusalem
10:55
INDUCED PLURIPOTENT STEM CELLS: IMPLICATIONS FOR CARDIAC RESEARCH
Lior Gepstein, Technion-Israel Institute of Technology
11:20
HUMAN EMBRYONIC STEM CELLS - FROM BENCH TO BEDSIDE
Benjamin Reubinoff, Hadassah Hebrew University Hospital
11:45
THE EPIGENETIC STABILITY OF PLURIPOTENT AND SOMATIC CELL STATES
Jacob H. Hanna, Weizmann Institute of Science
12:10
A LIBRARY OF ENDOGENOUSLY TAGGED FLUORESCENT PROTEINS IN EMBRYONIC STEM
CELL REVEALS A LINKER HISTONE CHAPERONE INVOLVED IN PLURIPOTENCY AND
DIFFERENTIATION
Eran Meshorer, The Hebrew University of Jerusalem
12:35
LINKING METABOLISM, PLURIPOTENCY AND EPIGENETIC CHANGES DURING EARLY
DIFFERENTIATION OF EMBRYONIC STEM CELLS
Arieh Moussaieff, Inserm, France and The Hebrew University of Jerusalem
10:30-13:00
Parallel Session B5:
Gene expression and RNA biology
Hall B - Herods Boutique
Chairpersons: Orna Elroy-Stein (Tel Aviv University) and Yaron Shav-Tal (Bar-Ilan University)
10:30
GENE EXPRESSION IS A CIRCULAR SYSTEM
Mordechai Choder, Technion-Israel Institute of Technology
10:55
CELL-CYCLE SPECIFIC TRANSLATIONAL CONTROL REVEALED BY A NOVEL PROTEOMIC
APPROACH
Orna Elroy-Stein, Tel Aviv University
11:20
A DUAL PROGRAM FOR PROTEIN TRANSLATION IN PROLIFERATION AND
DIFFERENTIATION
Yitzhak Pilpel, Weizmann Institute of Science
11:45
A ROLE FOR COPI IN THE CONTROL OF MRNA TRAFFICKING TO THE MITOCHONDRIA AND
IN MITOCHONDRIAL PHYSIOLOGY
Jeffrey Gerst, Weizmann Institute of Science
12:10
COMPREHENSIVE MAPPING OF RNA LOCALIZATION IN THE BACTERIAL CELL
Orna Amster-Choder, The Hebrew University of Jerusalem
12:35
THE LANDSCAPE OF ADENOSINE-TO-INOSINE RNA EDITING IN HUMAN
Erez Y. Levanon, Bar-Ilan University
8
Tuesday, February 11, 2014
10:30-13:00
Parallel Session C4:
Zoology and species preservation
Hall C - Herods Boutique
Chairpersons: Noga Kronfeld-Schor (Tel Aviv University) and Ran Nathan (The Hebrew University of
Jerusalem)
10:30
THE DILEMMA OF LIVING IN A GROUP STUDIED BY ON-BOARD AUDIO AND GPS
MONITORING OF BATS IN THE WILD
Yossi Yovel, Tel Aviv University
10:55
AN EMERGING MOVEMENT ECOLOGY PARADIGM FOR UNIFYING ORGANISMAL
MOVEMENT RESEARCH
Ran Nathan, The Hebrew University of Jerusalem
11:20
REINTRODUCTIONS AS A LARGE SCALE EXPERIMENT: THE DEVELOPMENT OF GENETIC
STRUCTURE WITHIN THE WILD ASS POPULATION IN ISRAEL
Shirli Bar-David, Ben-Gurion University of the Negev
11:45
MAMMALIAN "BAD" BREATH IS LIFE SAVING
Moshe Inbar, University of Haifa
12:10
THERMAL ECOLOGY OF A DIURNAL DESERT RODENT
Noga Kronfeld-Schor, Tel Aviv University
12:35
DEFENSE PHYSIOLOGY- IMPLICATIONS FOR PREY TROPHIC FUNCTION AND NUTRIENT
RECYCLING
Dror Hawlena, The Hebrew University of Jerusalem
10:30-13:00
Parallel Session F5:
Formation of functional neural networks
Hall D - Dan
Chairpersons: Avihu Klar (The Hebrew University-Hadassah Medical School) and Avraham Yaron
(Weizmann Institute of Science)
10:30
FUNCTIONAL INTEGRATION OF ADULT BORN NEURONS INTO THE MOUSE OLFACTORY
BULB
Adi Mizrahi, The Hebrew University of Jerusalem
10:55
VISUALIZING SINGLE CIRCUITS AND SYNAPSES IN LIVE MODEL ANIMALS FOR BRAIN
DISORDERS
Lior Appelbaum, Bar-Ilan University
11:20
PLEXIN-A4 CONTROLES DIVERSE CELLULAR RESPONSES IN DEVELOPING MAMMALIN
NEURONS THROUGH DISTINCT SIGNALING DOMAINS
Avraham Yaron, Weizmann Institute of Science
11:45
SEXUAL DEPRIVATION INCREASES ETHANOL INTAKE AND MODULATES SOCIAL
AVOIDANCE BEHAVIOR IN DROSOPHILA
Galit Shohat-Ophir, Bar-Ilan University
12:10
MOLECULAR MECHANISMS OF NEURONAL REMODELING
Oren Schuldiner, Weizmann Institute of Science
12:35
MOLECULAR AND MECHANISMS THAT CONTROL NEURONAL WIRING IN THE SPINAL
CORD
Avihu Klar, The Hebrew University-Hadassah Medical School
9
Tuesday, February 11, 2014
10:30-13:00
Parallel Session D4:
From basic science to clinical immunology
Hall E - Dan
Chairpersons: Eran Elinav (Weizmann Institute of Science) and Idit Shachar (Weizmann Institute of Science)
10:30
NEIGHBORLY RELATIONS: HOST MICROBIOTA INTERACTIONS IN HEALTH AND DISEASE
Eran Elinav, Weizmann Institute of Science
10:55
HUMAN IKKβ DEFICIENCY MANIFESTED IN LATE INFANCY BY DISSEMINATED
MYCOBACTERIAL INFECTION
Dror Mevorach, Hadassah Hebrew University Hospital
11:20
HARNESSING THE BIOLOGY OF ECM REMODELING FOR THERAPEUTIC APPLICATIONS IN
CLINICAL IMMUNOLOGY
Irit Sagi, Weizmann Institute of Science
11:45
THE CXCR4 ANTAGONIST EFFICIENTLY INDUCES NORMAL STEM CELL MOBILIZATION
AND APOPTOSIS OF AML CELLS IN VIVO
Amnon Peled, Hadassah Hebrew University Hospital
12:10
TUMOR-MICROENVIRONMENT INTERACTIONS IN LYMPH NODES OF CHRONIC
LYMPHOCYTIC LEUKEMIA MEDIATE B-CELL RECEPTOR ACTIVATION, NF-kappaB
SIGNALING AND PROMOTE TUMOR PROLIFERATION
Yair Herishanu, Tel Aviv Sourasky Medical Center
12:35
MOLECULAR MECHANISMS REGULATING B CELL SURVIVAL IN HEALTH AND DISEASE
Idit Shachar, Weizmann Institute of Science
10:30-13:00
Parallel Session D1:
Molecular, cellular and systems biology of microbes
Hall F - Dan
Chairpersons: Shoshy Altuvia (The Hebrew University of Jerusalem) and Nathalie Q. Balaban (The Hebrew
University of Jerusalem)
10:30
MANIPULATION OF BACILLUS SUBTILIS BIOFILMS BY ITS EUKARYOTIC HOST
Ilana Kolodkin-Gal, Weizmann Institute of Science
10:55
CRISPR ADAPTATION IN ESCHERICHIA COLI
Udi Qimron, Tel Aviv University
11:20
THE ROLE OF PHOSPHATE IN PSEUDOMONAS AERUGINOSA SWARMING MOTILITY AND
BIOFILM FORMATION
Ehud Banin, Bar-Ilan University
11:45
PLASTICITY IN BACTERIAL CHEMOSENSORY ARRAYS
Ady Vaknin, The Hebrew University of Jerusalem
12:10
ELEVATED MUTAGENESIS DOES NOT EXPLAIN THE INCREASED FREQUENCY OF
ANTIBIOTIC RESISTANT MUTANTS IN STARVED AGING COLONIES
Ruth Hershberg, Technion-Israel Institute of Technology
12:35
QUANTITATIVE ANALYSES OF GROWTH-ARRESTED BACTERIA AND THE EVOLUTION OF
ANTIBIOTIC TOLERANCE
Nathalie Q. Balaban, The Hebrew University of Jerusalem
10
Tuesday, February 11, 2014
10:30-13:00
Parallel Session A2:
Design principles of gene regulatory circuits
Hall H - Royal Beach
Chairpersons: Nir Friedman (The Hebrew University of Jerusalem) and Irit Gat-Viks (Tel Aviv University)
This session is sponsored by the I-CORE Chromatin and RNA Gene Regulation
10:30
DYNAMICS AND INFORMATION PROCESSING OF SIGNALING AND EXPRESSION
RESPONSES TO ENVIRONMENTAL CHANGES
Iftach Nachman, Tel Aviv University
10:55
A NETWORK BIOLOGY APPROACH TO DECIPHER THE TISSUE-SPECIFIC MANIFESTATION
OF HEREDITARY DISEASES
Esti Yeger-Lotem, Ben-Gurion University of the Negev
11:20
CLK MRNA TURNOVER DE-NOISES CIRCADIAN TRANSCRIPTION IN TIME AND SPACE
Sebastian Kadener, The Hebrew University of Jerusalem
11:45
DUAL FUNCTIONS OF THE TRANSCRIPTIONAL SUBUNIT TAF7L IN ADIPOCYTE
DIFFERENTIATION
Tommy Kaplan, The Hebrew University of Jerusalem
12:10
EMBEDDING GENETIC VARIANTS WITHIN THE CONTEXT OF THE CELLULAR CIRCUIT
Irit Gat-Viks, Tel Aviv University
12:35
CHROMATIN IN ACTION: DYNAMIC VIEW OF HISTONE MODIFICATIONS DURING
TRANSCRIPTIONAL REPROGRAMING
Nir Friedman, The Hebrew University of Jerusalem
10:30-13:00
Parallel Session F6:
Interphase between developmental and cell biology
Hall I - Royal Beach
Chairpersons: Benjamin Podbilewicz (Technion-Israel Institute of Technology) and Talila Volk (Weizmann
Institute of Science)
10:30
LAMIN AND ATX-2 REGULATE THE SIZE OF DIETARY RESTRICTED ANIMALS
Yosef Gruenbaum, The Hebrew University of Jerusalem
10:55
MUSCLE GUIDANCE TOWARDS TENDON CELLS: SHORT RANGE SIGNALING BY SLIT/ROBO
SIGNALING PATHWAY
Talila Volk, Weizmann Institute of Science
11:20
LYSYL OXIDASE REGULATES MYOFIBER:CONNECTIVE TISSUE CROSSTALK DURING
MYOGENESIS
Peleg Hasson, Technion-Israel Institute of Technology
11:45
REGULATION OF MORPHOGENESIS BY THE ULP-2 SUMO PROTEASE
Limor Broday, Tel Aviv University
12:10
Sept4/ARTS REGULATES STEM CELL APOPTOSIS AND SKIN REGENERATION
Yaron Fuchs, The Rockefeller University and Howard Hughes Medical Institute, NY, USA
12:35
FORMATION AND MAINTENANCE OF SARCOMERIC THIN-FILAMENT ARRAYS IN
DROSOPHILA
Benny Shilo, Weizmann Institute of Science
11
Tuesday, February 11, 2014
10:30-13:00
Parallel Session G5:
Molecular basis of neurodegeneration
Hall J - Royal Beach
Chairpersons: Ruth Gabizon (Hadassah Hebrew University Hospital) and Hermona Soreq (The Hebrew
University of Jerusalem)
10:30
CAUSES AND CONSEQUENCES OF microRNA DYSREGULATION IN NEURODEGENERATION
Eran Hornstein, Weizmann Institute of Science
10:55
THE SERINE SHUTTLE BETWEEN GLIA AND NEURONS: IMPLICATIONS FOR
NEUROTRANSMISSION AND NEURODEGENERATION
Herman Wolosker, Technion-Israel Institute of Technology
11:20
NOVEL POMEGRANATE OIL NANO-EMULSIONS FOR THE PREVENTION AND TREATMENT
OF NEURODEGENERATIVE DISEASES: THE CASE OF GENETIC CJD
Ruth Gabizon, Hadassah Hebrew University Hospital
11:45
MULTI-LEVELED RNA METABOLISM ERRORS IN ALZHEIMER'S DISEASE
Hermona Soreq, The Hebrew University of Jerusalem
12:10
ELUCIDATING THE ROLE OF ENVIRONMENTAL ENRICHMENT IN MITIGATING ALZHEIMER'S
DISEASE PATHOLOGY THROUGH microRNAs REGULATION
Uri Ashery, Tel Aviv University
12:35
MOLECULAR AND ELECTROPHYSIOLOGICAL SIGNALING FOLLOWING BRAIN VASCULAR
INJURY AND THEIR ROLE IN NEURODEGENERATION
Alon Friedman, Ben-Gurion University of the Negev
13:00-14:30
Lunch and Exhibition
14:30-16:00
PARALLEL SESSIONS: OP1, OP2, OP3, OP4, OP5, OP6, OP7, OP8, OP9
14:30-16:00
Parallel Oral Poster Session OP1:
New aspects of gene regulation
Chairperson: Naama Barkai (Weizmann Institute of Science)
Hall A - Herods Boutique
14:30
BIOLOGICAL CIRCUITS FOR PHYSIOLOGICAL DATA RECORDING INTO MAMMALIAN CELL
GENOMES
Naama Kanarek, Whitehead Institute for Biomedical Research, MA, USA
14:45
HIGH RESOLUTION MAPPING REVEALS A CONSERVED, WIDESPREAD, DYNAMIC
MEIOTICALLY REGULATED mRNA METHYLATION PROGRAM
Schraga Schwartz, Broad Institute of MIT and Harvard, MA, USA
15:00
WHAT DID WE LEARN ABOUT THE 'RAMP THEORY' IN THE PAST FOUR YEARS?
Tamir Tuller, Tel Aviv University
15:15
YEAST ADAPTATION TO STRESS: A ROLE FOR ANEUPLOIDY
Orna Dahan, Weizmann Institute of Science
15:30
DESIGN PRINCIPLES OF ALTRUISTIC BEHAVIOR
Ishay Ben-Zion, Tel Aviv University
15:45
DESIGN PRINCIPLES OF NONCONSENSUS PROTEIN-DNA BINDING
David Lukatsky, Ben-Gurion University of the Negev
12
Tuesday, February 11, 2014
14:30-16:00
Parallel Oral Poster Session OP2:
Experimental and modeling approaches for biomolecular interactions
Hall B - Herods Boutique
Chairperson: Ora Schueler-Furman (The Hebrew University of Jerusalem)
14:30
HERITABLE CUSTOM GENOMIC ENGINEERING IN C. ELEGANS VIA A CRISPR-CAS9
SYSTEM
Yonatan B. Tzur, Harvard Medical School, MA, USA
14:45
A COMPREHENSIVE TRNA DELETION LIBRARY UNRAVELS THE GENETIC ARCHITECTURE
OF THE TRNA POOL
Zohar Bloom-Ackerman, Weizmann Institute of Science
15:00
SPLICE VARIANTS THAT UNDERMINE THE MAIN ACTIVITY OF THEIR GENE IN CANCER
Miri Danan, Bar-Ilan University
15:15
WIDESPREAD EVIDENCE FOR DNA SHAPE DEPENDENT TRANSCRIPTION-FACTOR
BINDING PREFERENCES
Iris Dror, Technion-Israel Institute of Technology
15:30
A FULLY FLEXIBLE AND COMPLETELY BLIND PEPTIDE DOCKING APPROACH
Avraham Ben-Shimon, The Hebrew University of Jerusalem
15:45
DEVELOPING A POWERFUL IN SILICO TOOL FOR THE DISCOVERY OF NOVEL CASPASE-3
SUBSTRATES: A PRELIMINARY SCREENING OF THE HUMAN PROTEOME
Muneef Ayyash, Palestine Polytechnic University and Weizmann Institute of Science
14:30-16:00
Parallel Oral Poster Session OP3:
Plant signaling and development
Chairperson: Assaf Mosquna (The Hebrew University of Jerusalem)
Hall C - Herods Boutique
14:30
THE BALANCE BETWEEN CELL PROLIFERATION AND DIFFERENTIATION IS CONTROLLED
BY CONTRASTING SIGNALS FROM DIFFERENT TISSUES
Ayala Sela, Technion-Israel Institute of Technology
14:45
ROOT GROWTH IS MODULATED BY DIFFERENTIAL HORMONAL SENSITIVITY IN
NEIGHBORING CELLS
Yulia Fridman, Technion-Israel Institute of Technology
15:00
POST-TRANSLATIONAL REGULATION OF CONSTANS PROTEIN IN THE PHOTOPERIOD
PATHWAY OF ARABIDOPSIS THALIANA
Liron Sarid-Krebs, Max Planck Institute for Plant Breeding Research, Germany
15:15
STRESS RESPONSES IN THE BRYOPHYTE PHYSCOMITRELLA PATENS: MOLECULAR AND
GENOMIC APPROACHES
Michael Lawton, Rutgers University, NJ, USA
15:30
A NEWLY ISOLATED GREEN ALGA FROM DESERT CRUSTS - AN UNUSUAL COMBINATION
OF A UNIQUE SURVIVAL CAPABILITY AND RECORD HIGH GROWTH AND
PHOTOSYNTHETIC RATES
Haim Treves, The Hebrew University of Jerusalem
15:45
THE GLUCOSINOLATE BREAKDOWN PRODUCT INDOLE-3-CARBINOL ACTS AS AN AUXIN
ANTAGONIST IN ROOTS OF ARABIDOPSIS THALIANA
Ella Katz, Tel Aviv University
13
Tuesday, February 11, 2014
14:30-16:00
Parallel Oral Poster Session OP4:
From cell to organism behavior
Chairperson: Eli Arama (Weizmann Institute of Science)
Hall D - Dan
14:30
IMPAIRMENTS OF BEHAVIOR AND NEURON MORPHOLOGY IN CHD5 DEFICIENT MICE
Guy Horev, Cold Spring Harbor Laboratory, NY, USA
14:45
CORTICAL CIRCUITS UNDERLYING GENERALIZATION OF CONDITIONED FEAR
Mark Aizenberg, University of Pennsylvania, PA, USA
15:00
LIVE IMAGING OF SLEEP DEPENDENT AND RHYTHMIC SYNAPTIC PLASTICITY IN
ZEBRAFISH
Idan Elbaz, Bar-Ilan University
15:15
THE C. ELEGANS EMBRYONIC GERM LAYERS DIFFERENTIATE IN THE ORDER OF THEIR
EVOLUTIONARY APPEARANCE
Tamar Hashimshony, Technion-Israel Institute of Technology
15:30
DAP5 MEDIATED TRANSLATION CONTROL OF HUMAN EMBRYONIC STEM CELL
DIFFERENTIATION
Yael Yoffe, Weizmann Institute of Science
15:45
EMERGING ROLE OF microRNA PATHEWAY IN REGULATION OF PRIMED PLURIPOTENT
STATE
Abed AlFatah Mansour, Weizmann Institute of Science
14:30-16:00
Parallel Oral Poster Session OP5:
Cellular signaling and beyond
Chairperson: Dan Levy (Ben-Gurion University of the Negev)
Hall E - Dan
14:30
HDAC10 IS INVOLVED IN NUTRITIONAL REGULATION OF GROWTH
Galit Pinto, Tel Aviv University
14:45
REGULATION OF ERK1C BY MITOTIC CDK1
Inbal Wortzel, Weizmann Institute of Science
15:00
VAV1 MEDIATES TUMOR-MICROENVIRONMENT CROSS-TALK VIA GROWTH FACTOR
SECRETION
Shulamit Sebban, The Hebrew University of Jerusalem
15:15
THE CONFORMATIONAL LANDSCAPE OF GAMMA-SECRETASE IS ALTERED BY AN
ALZHEIMER DISEASE CAUSING MUTATION
Nadav Elad, KU Leuven and VIB, Belgium
15:30
STRUCTURAL BASIS FOR DISRUPTING POLYUBIQUITIN SIGNALING WITH SMALL
MOLECULES
Mark A. Nakasone, University of Maryland College Park, MD, USA
15:45
DISCOVERING NOVEL INTERACTIONS WITHIN THE PROTEOMICS MAP OF CELL DEATH
USING A PROTEIN FRAGMENT COMPLEMENTATION SCREEN
Yuval Gilad, Weizmann Institute of Science
14
Tuesday, February 11, 2014
14:30-16:15
Parallel Oral Poster Session OP6:
Control of microbial growth and death and the immune system
Chairperson: Shulamit Katzav-Shapira (The Hebrew University of Jerusalem)
Hall F - Dan
14:30
STUDY OF GROWTH CONTROL IN OBLIGATE PREDATORY BACTERIA
Or Rotem, The Hebrew University of Jerusalem
14:45
ATMOSPHERIC CO2 SEQUESTRATION THROUGH BIOMINERALIZATION HAS A PIVOTAL
ROLE IN BIOFILM DEVELOPMENT
Odelia Sibony Nevo, Weizmann Institute of Science
15:00
ORIGIN OF APOPTOSIS? SIMILARITIES BETWEEN BACTERIAL PROGRAMMED CELL
DEATH AND MITOCHONDRIA SWELLING
Ronen Hazan, Harvard Medical School, Massachusetts General Hospital, Shriners Hospitals for
Children Boston, MA, USA and The Hebrew University of Jerusalem
15:15
A NEW PHAGE RESISTANCE SYSTEM THAT IS WIDESPREAD IN MICROBIAL GENOMES
Tamara Goldfarb, Weizmann Institute of Science
15:30
BLOCKADE OF IL-10 LOOP UNLEASHES A TH17-POLARIZATION FEATURE IN LPSACTIVATED DENDRITIC CELLS
Irit Carmi-Levy, Curie, France
15:45
WHOLE BLOOD TARGETING AND ACTIVATION OF MONOCYTES WITH TLR7 AGONIST
FORMULATED IN CATIONIC LIPOSOMES
Daniel Zucker, Technical University of Denmark, Denmark
16:00
CONTAGIOUS CANNIBALISM IN INSECTS
Asaf Sadeh, University of California at Davis, CA, USA
14:30-16:00
Parallel Oral Poster Session OP7:
Cellular mechanisms and bioengineering approaches for disease therapy
Hall H - Royal Beach
Chairperson: Ofra Benny (The Hebrew University of Jerusalem)
14:30
SELF-ASSEMBLY OF AROMATIC DIPEPTIDES AND AMINO ACID: FROM
NANOTECHNOLOGY TO METABOLIC AGGREGATION DISEASES
Lihi Adler-Abramovich, Tel Aviv University
14:45
METABOLIC REGULATION OF LEPTIN AND INSULIN SIGNALING IN VIVO BY PROTEIN
TYROSINE PHOSPHATASE EPSILON
Ari Elson, Weizmann Institute of Science
15:00
IN VIVO TARGETING OF HYDROGEN PEROXIDE BY CELL-PENETRATING PEPTIDES
Roy Weinstain, University of California at San Diego, CA, USA
15:15
STEM CELL DERIVED NANO- VESICLES, A NEW DELIVERY PLATFORM FOR CANCER
TARGETED THERAPY
Naama Toledano-Furman, Technion-Israel Institute of Technology
15:30
THE ROLE OF THE QUIESCENCE INDUCER, SLFN2, IN T-ALL DEVELOPMENT
Michael Berger, The Hebrew University-Hadassah Medical School
15:45
p53 DEPLETION RESCUES MICE FROM CATECHOLAMINE DEPENDENT LIVER METABOLIC
STRESS
David Knigin, The Hebrew University-Hadassah Medical School and Hadassah Hebrew University
Hospital
15
Tuesday, February 11, 2014
14:30-16:00
Parallel Oral Poster Session OP8:
Molecular reprogramming in tumor and stromal cells
Chairperson: Uri Nir (Bar-Ilan University)
Hall I - Royal Beach
14:30
INHIBITING DISULFIDE FORMATION IN THE EXTRACELLULAR MATRIX TO DISRUPT
STROMAL SUPPORT OF TUMOR CELL SURVIVAL AND METASTASIS
Tal Ilani, Weizmann Institute of Science
14:45
CONTROLLING THE EXTRACELLULAR FUNCTION OF LYSYL OXIDASE LIKE PROTEIN 2 BY
MONOCLONAL ANTIBODIES HAS THERAPEUTIC POTENTIAL ON CELL INVASION AND
ANGIOGENESIS
Moran Grossman, Ruhr University, Germany
15:00
FUNCTIONAL CROSSTALK BETWEEN THE TUMOR SUPPRESSOR WWOX AND HIF1a
REGULATES GLUCOSE HOMEOSTASIS
Rami I. Aqeilan, The Hebrew University-Hadassah Medical School
15:15
IF YOU CAN'T BEAT THEM CHANGE THEM: A NEW WAY OF THINKING ABOUT TUMOR
THERAPY - LESSONS FROM C. ELEGANS
Mor Levi-Ferber, Bar-Ilan University
15:30
STUDYING P53 AS A KEY REGULATOR OF CANCER CELL METABOLISM
Inbal Mor, The Beatson Institute for Cancer Research, UK
15:45
HOW CANCER HIJACKS THE NORMAL TRANSLATION MACHINERY
Hila Gingold, Weizmann Institute of Science
14:30-16:00
Parallel Oral Poster Session OP9:
Cell biology and physiology
Chairperson: Elior Peles (Weizmann Institute of Science)
Hall J - Royal Beach
14:30
GLOBAL SELF-ORGANIZATION OF THE ACTIN CYTOSKELETON
Alexander D. Bershadsky, National University of Singapore, Singapore and Weizmann Institute of
Science
14:45
THE ZINC SENSING RECEPTOR, ZNR/GPR39, ENHANCES FORMATION OF THE INTESTINAL
EPITHELIAL BARRIER
Limor Cohen, Ben-Gurion University of the Negev
15:00
THE TUMOR SUPPRESSOR LGL1: A REGULATOR OF FRON-REAR POLARITY OF
MIGRATING CELLS
Shoshana Ravid, The Hebrew University of Jerusalem
15:15
TARGETING TO THE ER: UNCOVERING ELEMENTS OF AN SRP-INDEPENDENT PATHWAY
Naama Aviram, Weizmann Institute of Science
15:30
CRITICAL ROLE FOR CYCLOPHILIN CHAPERONES IN FOLDING LOCALIZATION AND
FUNCTION OF PRESENILIN 1 AND 2
Tziona Ben-Gedalya, The Hebrew University-Hadassah Medical School
15:45
ULP-4 DE-SUMOYLATES HMGS-1 TO REGULATE C.ELEGANS BIOENERGETICS IN AGING
AND DEVELOPMENT
Amir Sapir, California Institute of Technology and Howard Hughes Medical Institute, CA, USA
16:00-16:30
Coffee Break and Exhibition
16
Tuesday, February 11, 2014
16:30-19:00
PARALLEL SESSIONS: K2, F2, C6, G1, E2, A3, B7, B6, C5, E3
16:30-19:00
Parallel Session K2:
Translational science
Chairperson: Amir Naiberg (Weizmann Institute of Science)
Hall A - Herods Boutique
16:30
Introduction
Amir Naiberg, Weizmann Institute of Science
16:35
Michael Hayden, President of Global R&D and Chief Scientific Officer, Teva Pharmaceutical
Industries
16:50
Ajay Gautam, Executive Director, Head of Collaborations, Asia and Emerging Markets, AstraZeneca
17:05
Yaacov Michlin, CEO Yissum Research Development Company, The Hebrew University of Jerusalem
17:20
Dietmar Gross, SVP Head of Global Development, Merck Serono Ltd.
17:35
Yoav I. Henis, Vice President for Research and Development, Tel Aviv University
17:50
Round table discussion
16:30-19:00
Parallel Session F2:
The stem cell niche: from bench to bedside
Hall B - Herods Boutique
Chairpersons: Lior Gepstein (Technion-Israel Institute of Technology) and Lilach Gilboa (Weizmann Institute
of Science)
16:30
DOES THE METABOLIC STATE DRIVE STEM CELL FATE?
Atan Gross, Weizmann Institute of Science
16:55
REGULATION OF NORMAL AND LEUKEMIC HUMAN STEM CELLS: DYNAMIC STEM CELL
INTERACTIONS WITH THE BONE MARROW MICRONEVIRONMENT
Tsvee Lapidot, Weizmann Institute of Science
17:20
ROLE FOR MICRORNAS IN PROTECTING THE STEM CELL NICHE FROM APOPTOSIS
Hila Toledano, University of Haifa and Technion-Israel Institute of Technology
17:45
COORDINATING SOMATIC DEVELOPMENT WITH GERM LINE STEM CELL ESTABLISHMENT
Lilach Gilboa, Weizmann Institute of Science
18:10
IN VIVO MODELING OF DISEASES AND CANCERS ORIGINATING FROM THE NEURAL
CREST BY MOUSE-HUMAN NEURAL CREST CHIMERAS
Malkiel Cohen, The Whitehead Institute for Biomedical Research, MA, USA
18:35
GUT HOMEOSTASIS: A GENETIC NETWORK THAT MAINTAINS THE DIFFERENTIATED
STATE
Amir Orian, Technion-Israel Institute of Technology
17
Tuesday, February 11, 2014
16:30-19:00
Parallel Session C6:
Ecology and marine life
Hall C - Herods Boutique
Chairpersons: Debbie Lindell (Technion-Israel Institute of Technology) and Assaf Vardi (Weizmann Institute
of Science)
16:30
IS THERE AN EVOLUTIONARY CONSERVED PROTEOME TEMPLATE OF AN OOCYTE?
Tamar Lotan, University of Haifa
16:55
HYDRODYNAMIC STARVATION DURING THE CRITICAL PERIOD OF LARVAL FISHES
Roi Holzman, IUI Eilat and Tel Aviv University
17:20
THE LANGUAGES SPOKEN IN THE WATER BODY: WHAT DETERMINES WHO IS THERE OR
THE BIOLOGICAL ROLE OF SECONDARY METABOLITES INCLUDING TOXINS
Aaron Kaplan, The Hebrew University of Jerusalem
17:45
DIFFERENT INFECTION PROPERTIES AND ENVIRONMENTAL ABUNDANCES AMONG
DISTINCT LINEAGES OF T7-LIKE MARINE CYANOPODOVIRUSES
Debbie Lindell, Technion-Israel Institute of Technology
18:10
REDOX-BASES SENSING OF ENVIRONMENTAL STRESS- FROM ORGANELLE SIGNALING
TO CELL FATE DECISION
Assaf Vardi, Weizmann Institute of Science
18:35
THE ROLE OF THE MITOCHONDRIAL ALTERNATIVE OXIDASE IN THE ADAPTATION OF
DIATOMS TO CHANGING ENVIRONMENTAL CONDITIONS
Omer Murik, Institut de Biologie de l’Ecole Normale Supérieure (IBENS), France
16:30-19:00
Parallel Session G1:
The tumor and the host
Hall D - Dan
Chairpersons: Michal Neeman (Weizmann Institute of Science) and Eli Pikarsky (The Hebrew University of
Jerusalem)
16:30
CANCER ASSOCIATED FIBROBLASTS CO-EVOLVE DURING BREAST CANCER
PROGRESSION
Neta Erez, Tel Aviv University
16:55
TUMOR MICROENVIRONMENT-MEDIATED CHEMORESISTANCE: NOVEL MECHANISMS
AND FUTURE DIRECTIONS
Ravid Straussman, Weizmann Institute of Science
17:20
BLUNTING HOST EFFECTS FOLLOWING ANTI-CANCER DRUG THERAPY: A PARADIGM
SHIFT IN THE TREATMENT OF CANCER
Yuval Shaked, Technion-Israel institute of Technology
17:45
SENESCENT CELLS UTILIZE DIRECT PROTEIN TRANSFER TO IMPACT THEIR
MICROENVIRONMENT
Valery Krizhanovsky, Weizmann Institute of Science
18:10
LYSOSOMAL PHOTODESTRUCTION: A NOVEL TROJAN HORSE APPROACH TO OVERCOME
CANCER MULTIDRUG RESISTANCE
Yehuda G. Assaraf, Technion-Israel Institute of Technology
18:35
ONCOGENE-INDUCED PLASTICITY AND CANCER STEM CELLS IN GLIOBLASTOMA
Dinorah Friedmann-Morvinski, The Salk Institute for Biological Studies, CA, USA
18
Tuesday, February 11, 2014
16:30-19:00
Parallel Session E2:
Reprogramming and bioengineering approaches for stem cell therapy
Hall E - Dan
Chairpersons: Joseph Itskovitz-Eldor (Technion-Israel Institute of Technology) and Shulamit Levenberg
(Technion-Israel Institute of Technology)
16:30
NEW CONCEPTS IN CULTURING HUMAN PLURIPOTENT STEM CELLS
Joseph Itskovitz-Eldor, Technion-Israel Institute of Technology
16:55
BIOACTIVE SCAFFOLDS FOR VASCULARIZATION OF ENGINEERED TISSUE
Shulamit Levenberg, Technion-Israel Institute of Technology
17:20
IDENTIFICATION AND UTILIZATION OF HEMATOPOIETIC STEM CELL'S GENES
Roi Gazit, Ben-Gurion University of the Negev
17:45
MESENCHYMAL REGULATION OF BETA CELL DEVELOPMENT AND FUNCTION
Limor Landsman, Tel Aviv University
18:10
CHOOSING THE BEST STEM CELLS FOR KIDNEY GENERATION AND REGENERATION
Benjamin Dekel, Sheba Medical Center and Tel Aviv University
18:35
WEANING AS A NOVEL MATURATION STEP OF PANCREATIC BETA CELLS
Miri Stolovich-Rain, The Hebrew University-Hadassah Medical School
16:30-19:00
Parallel Session A3:
Transcriptome dynamics
Hall F - Dan
Chairpersons: Rotem Sorek (Weizmann Institute of Science) and Itai Yanai (Technion-Israel Institute of
Technology)
16:30
EVOLUTION OF DEVELOPMENTAL GENE PATHWAYS THROUGHOUT THE ANIMAL
KINGDOM
Itai Yanai, Technion-Israel Institute of Technology
16:55
RIBOSWITCH DISCOVERY IN BACTERIA VIA 3P-SEQ
Rotem Sorek, Weizmann Institute of Science
17:20
PROMOTER NUCLEOSOMES SHAPE THE EVOLUTION OF GENE EXPRESSION
Naama Barkai, Weizmann Institute of Science
17:45
TRANSCRIPTION NETWORKS PROVIDE A WINDOW INTO THE NEURAL CIRCUITRY OF
ADDICTION
Ami Citri, The Hebrew University of Jerusalem
18:10
BIDIRECTIONAL INTERACTION BETWEEN MELANOMA CELLS AND THE
MICROENVIRONMENT
Carmit Levy, Tel Aviv University
18:35
EVOLUTIONARY PATTERNS OF ESCHERICHIA COLI SMALL RNAS AND THEIR
REGULATORY INTERACTIONS
Asaf Peer, The Hebrew University of Jerusalem
19
Tuesday, February 11, 2014
16:30-19:00
Parallel Session B7:
Autophagy and intracellular membrane/protein dynamics
Hall G - Dan
Chairpersons: Adi Kimchi (Weizmann Institute of Science) and Zvulun Elazar (Weizmann Institute of Science)
16:30
DUAL TARGETING OF PROTEINS IN EUKARYOTES: MECHANISM, EVOLUTION AND
FUNCTION
Ophry Pines, The Hebrew University of Jerusalem
16:55
FACTORS CONTROLLING TRANSLATION IN THE VICINITY OF MITOCHONDRIA
Yoav Arava, Technion-Israel Institute of Technology
17:20
MUTANT HUNTINGTIN AGGREGATION AND ITS EFFECT ON ENDOPLASMIC RETICULUM
DYNAMICS AND STRESS
Gerardo Lederkremer, Tel Aviv University
17:45
A ROLE FOR MITOCHONDRIAL DYNAMICS IN THE SEGREGATION OF MITOCHONDRIAL
MATRIX PROTEINS DURING STATIONARY PHASE MITOPHAGY
Hagai Abeliovich, The Hebrew University of Jerusalem
18:10
ATG8 PROTEINS AND AUTOPHAGOSOME FORMATION
Zvulun Elazar, Weizmann Institute of Science
18:35
DISCOVERING NOVEL PROTEIN-PROTEIN INTERACTIONS IN AUTOPHAGY AND IN ITS
CROSS TALK WITH APOPTOSIS
Adi Kimchi, Weizmann Institute of Science
16:30-19:00
Parallel Session B6:
Protein modification and degradation
Hall H - Royal Beach
Chairpersons: Michael Glickman (Technion-Israel Institute of Technology) and Michal Sharon (Weizmann
Institute of Science)
16:30
PROTEASOMAL DEGRADATION OF IDPs; KEY CELLULAR INSTRUCTIVE PROTEINS
Yosef Shaul, Weizmann Institute of Science
16:55
THE PARKINSON ASSOCIATED PROTEIN, DJ-1, REGULATES THE 20S PROTEASOME
Michal Sharon, Weizmann Institute of Science
17:20
PROTEIN TAGGING AND DEGRADATION BY THE MYCOBACTERIAL PUP-PROTEASOME
SYSTEM
Eyal Gur, Ben-Gurion University of the Negev
17:45
FORMATION AND DISSOCIATION OF PROTEASOME STORAGE GRANULES ARE
REGULATED BY CYTOSOLIC PH
Shay Ben-Aroya, Bar-Ilan University
18:10
REGULATION OF α-SYNUCLEIN DEGRADATION: IMPLICATIONS TO THE PATHOGENESIS
OF PARKINSON'S DISEASE
Simone Engelender, Technion-Israel Institute of Technology
18:35
THE 26S PROTEASOME IS A SENSOR FOR MITOCHONDRIA DYSFUNCTION
Michael Glickman, Technion-Israel Institute of Technology
20
Tuesday, February 11, 2014
16:30-19:00
Parallel Session C5:
Biotechnology and biopharming
Hall I - Royal Beach
Chairpersons: Oded Shoseyov (The Hebrew University of Jerusalem) and Iftach Yacoby (Tel Aviv University)
16:30
STUDYING DESIGN PRINCIPLES OF BISPECIFIC ANTIBODIES
Itai Benhar, Tel Aviv University
16:55
MOVING MOLECULAR IMMUNOLOGY AND ANTIBODY ENGINEERING INTO NOVEL
THERAPEUTICS
Yoram Reiter, Technion-Israel Institute of Technology
17:20
FUNCTIONAL IGG MULTIMERS: FORMATION AND SUSTAINED RELEASE OF ACTIVE
ANTIBODIES
Yaron Dekel, MIGAL-Galilee Research Institute
17:45
NANO BIO INSPIRED COMPOSITE MATERIALS FOR THE FUTURE
Oded Shoseyov, The Hebrew University of Jerusalem
18:10
OPTIMIZING PHOTOSYNTHESIS TO CREATE HYDROGEN POWER
Iftach Yacoby, Tel Aviv University
18:35
ENGINEERING OF ELECTRICITY AND HYDROGEN PRODUCING PHOTOCELL BASED ON
PHOTOSYNTHESIS
Roy I. Pinhassi, Technion-Israel Institute of Technology
16:30-19:00
Parallel Session E3:
Nanotherapeutics and targeted drug delivery
Hall J - Royal Beach
Chairpersons: Ayelet David (Ben-Gurion University of the Negev) and Dan Peer (Tel Aviv University)
16:30
NANO-SCALE SYSTEMS FOR TARGETED DELIVERY OF DRUGS AND NEUCLOTIDES
Joseph Kost, Ben-Gurion University of the Negev
16:55
DOXIL, THE FIRST FDA-APPROVED NANO-DRUG: MECHANISM OF DRUG RELEASE IN
TUMORS WITH RELATIONSHIP TO TUMOR METABOLISM
Yechezkel Barenholz, The Hebrew University-Hadassah Medical School
17:20
IDENTIFYING A MICRORNA SIGNATURE FOR TUMOR DORMANCY AS A BASIS FOR THE
DEVELOPMENT OF A THERANOSTIC NANOMEDICINE
Ronit Satchi-Fainaro, Tel Aviv University
17:45
TARGETED POLYMER CONJUGATES FOR COLORECTAL CANCER THERAPY AND IMAGING
Ayelet David, Ben-Gurion University of the Negev
18:10
TARGETED DRUG DELIVERY AND PERSONALIZED MEDICINE: FROM CHEMOTHERAPY TO
NANOBOTS
Avi Schroeder, Technion-Israel Institute of Technology
18:35
HARNESSING RNAi-BASED NANOMEDICINES FOR PRECISION MEDICINE
Dan Peer, Tel Aviv University
19:00-21:00
Poster Session A and Buffet Dinner
21
Isrotel Sport Club
Wednesday, February 12, 2014
08:30-09:30
Plenary 3
Chairperson: Karen B. Avraham (Tel Aviv University)
08:30
Hall A - Herods Boutique
MICRORNAS, POLY(A) TAILS, AND A DEVELOPMENTAL SWITCH IN THE NATURE OF
TRANSLATIONAL CONTROL
David Bartel, HHMI, Whitehead Institute, MIT, MA, USA
09:30-10:30
Plenary 4
Chairperson: Yinon Ben-Neriah (The Hebrew University of Jerusalem)
09:30
Hall A - Herods Boutique
LGR5 STEM CELLS IN SELF-RENEWAL AND CANCER
Hans Clevers, Royal Netherlands Academy of Arts and Sciences and University Medical Center
The Netherlands
10:30-11:00
Coffee Break and Exhibition
11:00-13:30
PARALLEL SESSIONS: A4, G2, C1, A7, K1, B1, D5, E4, F3, B8
11:00-13:30
Parallel Session A4:
Epigenetics, chromatin organization and folding
Hall A - Herods Boutique
Chairpersons: Yehudit Bergman (The Hebrew University-Hadassah Medical School) and Amos Tanay
(Weizmann Institute of Science)
11:00
PROGRAMMING DNA METHYLATION DURING DEVELOPMENT
Howard Cedar, The Hebrew University of Jerusalem
11:25
FROM CHROMATIN TO CANCER: STUDYING THE BIOLOGY OF HISTONE DEMETHYLATION
Nabieh Ayoub, Technion-Israel Institute of Technology
11:50
PALEO-EPIGENETICS: RECONSTRUCTING THE DNA METHYLATION MAPS OF EXTINCT
HUMAN GROUPS
David Gokhman, The Hebrew University of Jerusalem
12:15
NON-MENDELIAN MECHANISMS OF INHERITANCE OF A RESPONSE TO TOXIC STRESS
Yoav Soen, Weizmann Institute of Science
12:40
SINGLE CELL APPROACHES TO CELL STATE AND EPIGENETIC MEMORY
Amos Tanay, Weizmann Institute of Science
13:05
EPIGENETIC PROGRAMMING OF ALLELIC EXCLUSION
Yehudit Bergman, The Hebrew University-Hadassah Medical School
22
Wednesday, February 12, 2014
11:00-13:30
Parallel Session G2:
Molecular pathogenesis of cancer
Hall B - Herods Boutique
Chairpersons: Shai Izraeli (Sheba Medical Center, Tel Aviv University) and Yardena Samuels (Weizmann
Institute of Science)
11:00
RNF20: AN EPIGENETIC TUMOR SUPPRESSOR
Moshe Oren, Weizmann Institute of Science
11:25
THE MOLECULAR BASIS FOR REPLICATION-INDUCED DNA DAMAGE IN EARLY STAGES OF
CANCER DEVELOPMENT
Batsheva Kerem, The Hebrew University of Jerusalem
11:50
CAN p53 SECURE THE GENOMIC FIDELITY OF STEM CELLS?
Varda Rotter, Weizmann Institute of Science
12:15
FUNCTIONAL GENOMICS AND MODELING OF CHILDHOOD LEUKEMIAS - LESSONS FORM
DOWN SYNDROME
Shai Izraeli, Sheba Medical Center and Tel Aviv University
12:40
WHOLE EXOME SEQUENCING IDENTIFIES RECURRENT FUNCTIONAL MUTATIONS IN
MELANOMA
Yardena Samuels, Weizmann Institute of Science
13:05
NON-INVASIVE MONITORING OF CANCER GENOMES IN PATIENT PLASMA USING
CIRCULATING TUMOUR DNA
Nitzan Rosenfeld, University of Cambridge, UK
11:00-13:30
Parallel Session C1:
Integration of plant developmental signaling pathways
Hall C - Herods Boutique
Chairpersons: Naomi Ori (The Hebrew University of Jerusalem) and Shaul Yalovsky (Tel Aviv University)
11:00
THE ROLE OF CYTOKININ AND AUXIN-RELATED PROGRAMS IN TOMATO FLOWERING
Yuval Eshed, Weizmann Institute of Science
11:25
UNDERSTANDING COORDINATED GROWTH THROUGH CELL-TYPE SPECIFIC ACTIVITY OF
BRASSINOSTEROIDS
Sigal Savaldi-Goldstein, Technion-Israel Institute of Technology
11:50
STUDYING HOW TOO MANY FRUIT INTERRUPT CYCLES OF REPRODUCTION IN FRUIT
TREES
Alon Samach, The Hebrew University of Jerusalem
12:15
AUXIN: ONE PLANT HORMONE - MANY DEVELOPMENTAL INPUTS AND OUTPUTS
Eilon Shani, Tel Aviv University
12:40
CELL-SPECIFIC REGULATION AND SIGNALLING IN THE PLANT CIRCADIAN SYSTEM
Rachel Green, The Hebrew University of Jerusalem
13:05
HORMONAL SIGNALS AND THE FATE OF MERISTEMS: FROM SYSTEMS BIOLOGY TO
BIOLOGY OF SYSTEMS
Eliezer Lifschitz, Technion-Israel Institute of Technology
23
Wednesday, February 12, 2014
11:00-13:30
Parallel Session A7:
Gene discovery and regulation in human disease
Hall D - Dan
Chairpersons: Lina Basel-Vanagaite (Tel Aviv University) and Orly Elpeleg (Hadassah Hebrew University
Hospital)
This session is dedicated to the memory of the late Prof. Yehudith Birk (The Hebrew University of Jerusalem,
Faculty of Agriculture, Food and Environment), Israel Prize Winner
11:00
WHOLE EXOME SEQUECING - A GAME CHANGER IN THE CLINIC
Orly Elpeleg, Hadassah Hebrew University Hospital
11:25
MUTATION PROFILING OF EXONIC-ENHANCERS USING MASSIVELY PARALLEL REPORTER
ASSAYS
Ramon Birnbaum, Ben-Gurion University of the Negev
11:50
IDENTIFICATION OF NEW GENES RELATED TO INTELLECTUAL DISABILITY BY NEXT
GENERATION SEQUENCING
Lina Basel-Vanagaite, Tel Aviv University
12:15
A NOVEL GENETIC BASIS FOR SYSTEMIC VASCULITIS: POLYARTERITIS NODOSA (PAN)
CAUSED BY RECESSIVE MUTATIONS ALTERING ADENOSINE DEAMINASE 2 (ADA2)
Ephrat Levy-Lahad, Shaare Zedek Medical Center
12:40
GENOTYPE-PHENOTYPE CORRELATIONS IN NEUROFIBROMATOSIS TYPE 1, PROVIDE
BETTER UNDERSTANDING OF THE DISORDER'S PATHOPHYSIOLOGY, AND IMPROVE
PATIENTS' CARE
Shay Ben-Shachar, Tel Aviv Sourasky Medical Center
13:05
IDENTIFICATION OF SMALL RNA PATHWAY GENES USING PATTERNS OF PHYLOGENETIC
CONSERVATION AND DIVERGENCES
Yuval Tabach, Harvard Medical School and Massachusetts General Hospital, MA, USA
11:00-13:30
Parallel Session K1:
Life science policy and research funding in Israel
Chairperson: Benjamin Geiger (Israel Science Foundation and Weizmann Institute of Science)
Hall E - Dan
11:00
Opening
Benjamin Geiger, Israel Science Foundation and Weizmann Institute of Science
11:05
Manuel Trajtenberg, Chairman of the Planning and Budgeting Committee (PBC) of the Council of
Higher Education (CHE) in Israel
11:25
Liat Maoz, Director of the Unit for Projects in Planning and Budgeting and Director of the I-CORE
program in the Planning and Budgeting Committee (PBC)
11:45
Ehud Gazit, Chief Scientist of the Ministry of Science and Technology (MOST)
12:05
Benjamin Geiger, Israel Science Foundation and Weizmann Institute of Science
12:25
Haim Garty, Vice President of the Weizmann Institute of Science
12:45
Galia Blum, The Hebrew University of Jerusalem
13:05
General discussion
24
Wednesday, February 12, 2014
11:00-13:30
Parallel Session B1:
Structure-function in atomic detail
Hall F - Dan
Chairpersons: Oded Livnah (The Hebrew University of Jerusalem) and Raz Zarivach (Ben-Gurion University
of the Negev)
11:00
STRUCTURAL STUDIES OF ANTI-HIV-1 NEUTRALIZING ANTIBODIES
Ron Diskin, Weizmann Institute of Science
11:25
UNFOLDOMICS OF THE CELLULAR STRESS RESPONSE - HOW DO INTRINSICALLY
DISORDERED CHAPERONES WORK?
Dana Reichmann, The Hebrew University of Jerusalem
11:50
PLATELETS AND CANCER: THE ROLE OF THE PLATELET-ACTIVATING RECEPTOR CLEC-2
Meytal Landau, Technion-Israel Institute of Technology
12:15
DISORDER AND STRUCTURE IN WASP-INTERACTING PROTEIN SHED LIGHT ON ITS
BIOLOGICAL FUNCTION
Jordan H. Chill, Bar-Ilan University
12:40
MECHANISMS FOR SENSING AND DECODING THE UBIQUITIN SIGNALS
Gali Prag, Tel Aviv University
13:05
ACTIVATION OF DIVALENT TRANSPORTER VIA STRUCTURE-FUNCTION STUDIES OF
MAGNETOSOME ASSOCIATED PROTEIN MamM
Raz Zarivach, Ben-Gurion University of the Negev
11:00-13:30
Parallel Session D5:
Pathogen innate immune interactions
Hall H - Royal Beach
Chairpersons: Anat A. Herskovits (Tel Aviv University) and Angel Porgador (Ben-Gurion University of the
Negev)
11:00
HOW DO PATHOGENS SENSE THEIR HOST?
Neta Sal-Man, Ben-Gurion University of the Negev
11:25
INHIBITION OF MICROBIAL SPREADING BY THE ARCHITECTURE OF AN AVIAN NEST
Ido Bachelet, Bar-Ilan University
11:50
MODULATION OF THE INFLAMMATORY RESPONSE BY ENTROPATHOGENIC BACTERIA
Ilan Rosenshine, The Hebrew University of Jerusalem
12:15
LISTERIA MONOCYTOGENES MDR TRANSPORTERS AND C-DI-AMP THAT CONTRIBUTE TO
TYPE I INTERFERONS INDUCTION, PLAY A ROLE IN CELL WALL REGULATION
Anat A. Herskovits, Tel Aviv University
12:40
HOW AN EXTRACELLULAR PATHOGENIC BACTERIUM ALTERS HOST METABOLISM TO
REGULATE ITS SENSING AND PROLIFERATION
Emanuel Hanski, National University of Singapore, Singapore and The Hebrew University of
Jerusalem
13:05
HOW DO HOSTS SENSE THEIR PATHOGEN
Angel Porgador, Ben-Gurion University of the Negev
25
Wednesday, February 12, 2014
11:00-13:30
Parallel Session E4:
Ion channels: a window for understanding cellular functions
Hall I - Royal Beach
Chairpersons: Nathan Dascal (Tel Aviv University) and Baruch Minke (The Hebrew University of Jerusalem)
This session is dedicated to the memory of the late Prof. Zvi Selinger (The Hebrew University of Jerusalem), a
pioneer in elucidating the G-Protein cycle
+
11:00
LITHIUM REGULATES K (GIRK) CHANNELS: MECHANISMS AND POSSIBLE LINK TO
BIPOLAR DISORDER
Nathan Dascal, Tel Aviv University
11:25
SODIUM FLUXES AND EXCITABILITY OF THIN NEURONAL PROCESSES
Ilya Fleidervish, Ben-Gurion University of the Negev
11:50
THE MULTI-FUNCTIONAL MITOCHONDRIAL CHANNEL VDAC1: FROM STRUCTURE TO
CANCER THERAPY
Varda Shoshan-Barmatz, Ben-Gurion University of the Negev
12:15
NEW INSIGHT ON THE GATING MECHANISM OF TRP CHANNELS
Baruch Minke, The Hebrew University of Jerusalem
12:40
VOLTAGE-GATED POTASSIUM CHANNEL AS A REGULATOR OF VESICLE PRIMING THAT
ENHANCES EXOCYTOSIS
Ilana Lotan, Tel Aviv University
13:05
REGULATION OF CELLULAR CALCIUM HOMEOSTASIS BY SARAF
Eitan Reuveny, Weizmann Institute of Science
11:00-13:30
Parallel Session F3:
Development of tissue architecture
Hall J - Royal Beach
Chairpersons: David Sprinzak (Tel Aviv University) and Elazar Zelzer (Weizmann Institute of Science)
11:00
HOW CELL FUSION SCULPTS ORGANS
Benjamin Podbilewicz, Technion-Israel Institute of Technology
11:25
EPIDERMAL CELL SHAPE DYNAMICS: FROM CELL FATE SPECIFICATION TO TISSUE
MORPHOGENESIS
Chen Luxenburg, Tel Aviv University
11:50
THE MECHANISM THAT REGULATES LONG BONE SCALING
Tomer Stern, Weizmann Institute of Science
12:15
THE DEPENDENCE OF NOTCH SIGNALING ON MEMBRANE DIFFUSION AND CONTACT
AREA
David Sprinzak, Tel Aviv University
12:40
DEVELOPMENTAL STRATEGIES OF INTESTINAL STEM CELLS
Shalev Itzkovitz, Weizmann Institute of Science
13:05
PAX6 REGULATES MELANOGENESIS IN THE RETINAL PIGMENTED EPITHELIUM THROUGH
FEED-FORWARD REGULATORY INTERACTIONS WITH MITF
Ruth Ashery-Padan, Tel Aviv University
26
Wednesday, February 12, 2014
11:00-13:30
Parallel Session B8:
Cytoskeleton dynamics in health and disease
Hall K - Herods Palace
Chairpersons: Leah Gheber (Ben-Gurion University of the Negev) and Arnon Henn (Technion-Israel Institute
of Technology)
11:00
CYTOSKELETAL SIGNALING IN CANCER METASTASIS
Hava Gil-Henn, Bar-Ilan University
11:25
THE MOLECULAR COMMUNICATION MECHANISM OF MOTOR NEURON SURVIVAL AND
SYNAPSE MAINTENANCE
Eran Perlson, Tel Aviv University
11:50
SUBTLE PERTURBATIONS TO MICROTUBULES UNCOUPLE CELL DIVISION FROM CELL
DIFFERENTIATION DURING ADVENTITIOUS ROOT FORMATION
Einat Sadot, Volcani Research Center
12:15
MEET GAS2L3, A CONSTRICTION SITE-ASSOCIATED PROTEIN ESSENTIAL FOR BRAIN
DEVELOPMENT
Amit Tzur, Bar-Ilan University
12:40
CARDIAC CELL MECHANOSENSING
Shelly Tzlil, Technion-Israel Institute of Technology
13:05
HOW NEURONAL INTERMEDIATE FILAMENTS SIDEARMS MODULATE THIER PHYSICAL
INTERACTION AND NETWORK STRUCTURE
Roy Beck, Tel Aviv University
13:30-15:00
Lunch and Exhibition
15:00-16:30
PARALLEL SESSIONS: OP10, OP11, OP12, OP13, OP14, OP15, OP16, OP17, OP18,
OP19
15:00-16:30
Parallel Oral Poster Session OP10:
Molecular events in cancer development and progression
Chairperson: Yona Keisari (Tel Aviv University)
Hall A - Herods Boutique
15:00
TRANSCRIPTION FACTOR/MIRNA AXIS BLOCKS MELANOMA INVASION PROGRAM BY MIR211 TARGETING NUAK1
Rachel E. Bell, Tel Aviv University
15:15
SYNPTOJANIN 2, A METASTASIS DRIVER, IS OVEREXPRESSED AND AMPLIFIED IN
ADVANCED BREAST CANCER
Nir Ben-Chetrit, Weizmann Institute of Science
15:30
IMMUNE-DEPENDENT LIVER MICRO-NICHES FOSTER TUMOR PROGENITOR CELLS
BEFORE THEY ACQUIRE SELF-SUFFICIENCY
Shlomi Finkin, The Hebrew University-Hadassah Medical School and Hadassah Hebrew University
Hospital
15:45
HOST RESPONSE TO CHEMOTHERAPY INDUCES PRO-TUMORIGENIC MESENCHYMAL
STEM CELLS ACTIVITIES LEADING TO PRESERVED CANCER STEM CELLS NICHE
Michael Timaner, Technion-Israel Institute of Technology
16:00
EFFECTS OF CELLULAR SENESCENCE, A TUMOR SUPPRESSIVE PROGRAM, ON CELL
AND TISSUE FUNCTION
Ronny Helman, The Hebrew University of Jerusalem
16:15
MTORC1 INHIBITION IS REQUIRED FOR SENSITIVITY TO PI3K P110ALPHA INHIBITORS IN
PIK3CA-MUTATED BREAST CANCER
Moshe Elkabets, Memorial Sloan Kettering Cancer Center, NY and Massachusetts General Hospital
Cancer Center, MA, USA
27
Wednesday, February 12, 2014
15:00-16:45
Parallel Oral Poster Session OP11:
Genomic and transcriptomic regulation
Chairperson: Yael Mandel-Gutfreund (Technion-Israel Institute of Technology)
Hall B - Herods Boutique
15:00
REPLICATION TIMING SHAPES REGIONAL GC CONTENT OF MAMMALIAN GENOMES
Yishai Yehuda, The Hebrew University-Hadassah Medical School
15:15
DNase-seq PREDICTS REGIONS OF ROTATIONAL NUCLEOSOME STABILITY ACROSS
DIVERSE HUMAN CELL TYPES
Deborah Winter, Duke University, NC, USA and Weizmann Institute of Science
15:30
CHARACTERIZATION OF AN EPIGENETIC SIGNATURE AT INTRAGENIC EXONS AND ITS
IMPLICATION FOR EXPRESSION
Idit Kosti, Technion-Israel Institute of Technology
15:45
SINGLE CELL ANALYSES UNCOVER CELL-TO-CELL VARIABILITY IN PRODUCTION OF
CHIMERIC TRANSCRIPTS BY TRANS-SPLICING
Milana Frenkel-Morgenstern, Spanish National Cancer Research Center (CNIO), Spain
16:00
COMPARATIVE TRANSCRIPTOMICS ACROSS THE PROKARYOTIC TREE OF LIFE
Ofir Cohen, Weizmann Institute of Science
16:15
tRNA GENES RAPIDLY CHANGE IN EVOLUTION TO MEET NOVEL TRANSLATIONAL
DEMANDS
Idan Frumkin, Weizmann Institute of Science
16:30
CELL TO CELL TRANSFER OF mRNA: A NEW MODE OF INTERCELLULAR COMMUNICATION
Gal Haimovich, Albert Einstein College of Medicine of Yeshiva University, NY, USA
15:00-16:30
Parallel Oral Poster Session OP12:
Integrative plant biology - from ecology to molecules
Chairperson: Nir Ohad (Tel Aviv University)
Hall C - Herods Boutique
15:00
A SINGLE TRANSCRIPTION FACTOR INDUCES PHASE TRANSITION AND APOMIXIS IN
MOSS, REPRESENTATIVE OF EARLY LAND PLANTS
Nir Ohad, FRIAS, Germany and Tel Aviv University
15:15
REDUCED EPIGENETIC CONSTRAINTS IN THE DESERT PLANT ZYGOPHYLLUM DUMOSUM
Gideon Grafi, Ben-Gurion University of the Negev
15:30
FROM A PLANT PHENOTYPE TO SEED DISPERSAL PATTERN
Eyal Zinger, Tel Aviv University
15:45
MODIFICATIONS OF CELL WALL PROPERTIES BY PRODUCTION OF RECOMBINANT
RESILIN COMPOSITES IN TRANSGENIC PLANTS
Itan Preis, The Hebrew University of Jerusalem
16:00
ENGINEERING FLOWERING PLANTS AND CELL CULTURES FOR HIGHER PRODUCTION OF
VALUABLE POLYPHENOL METABOLITES AS HEALTH PROMOTING ANTI-OXIDANTS AND
FRAGRANCE COMPOUNDS
Moran Oliva, Volcani Research Center and Weizmann Institute of Science
16:15
ZOOPLANKTON GRAZING AND BARCODE: ECOLOGICAL APPLICATIONS OF MOLECULAR
TOOLS
Sharon Mejer, Israel Oceanographic and Limnological Research
28
Wednesday, February 12, 2014
15:00-16:30
Parallel Oral Poster Session OP13:
Regulation of gene expression by signaling pathways
Chairperson: Tamar Juven-Gershon (Bar-Ilan University)
Hall D - Dan
15:00
MACROMOLECULAR CROWDING ALTERS THE BINDING PROPERTIES OF PROTEIN
COMPLEXES, THEIR ACTIVITIES, AND THEIR STRUCTURES
Barak Akabayov, Harvard Medical School, MA, USA
15:15
ON THE FLY DATABASE - STRUCTURAL BASIS TO STUDY TF's DNA BINDING SPECIFICITY
Shula Shazman, Columbia University and Howard Hughes Medical Institute, NY, USA
15:30
CORE PROMOTER COMPOSITION PLAYS A CRITICAL FUNCTION IN THE REGULATION OF
GENE EXPRESSION OF DROSOPHILA DORSAL TARGET GENES
Yonathan Zehavi, Bar-Ilan University
15:45
THE NUCLEAR TRANSLOCATION OF ERK AS A NOVEL TARGET FOR CANCER THERAPY
Karen Flores, Weizmann Institute of Science
16:00
LYSINE METHYLATION SIGNALING AT CHROMATIN IN INFLAMMATION AND CANCER
Dan Levy, Ben-Gurion University of the Negev
16:15
PROMISCUOUS RNA BINDING BY PRC2: THE JUNK MAIL MODEL FOR THE MAINTENANCE
OF REPRESSED CHROMATIN
Chen Davidovich, University of Colorado Boulder, CO, USA
15:00-16:30
Parallel Oral Poster Session OP14:
Molecular aspects of pathogen-cell interactions
Chairperson: Eran Bacharach (Tel Aviv University)
Hall E - Dan
15:00
PATHOGENS USE STRUCTURAL MIMICRY OF NATIVE HOST LIGANDS AS A MECHANISM
OF HOST RECEPTOR ENGAGMENT
Nir Drayman, The Hebrew University-Hadassah Medical School
15:15
LDL RECEPTOR AND ITS FAMILY MEMBERS ARE THE CELLULAR RECEPTORS FOR
VESICULAR STOMATITIS VIRUS AND VSV-G-PSEUDOTYPED LENTIVIRAL VECTORS
Danit Finkelshtein, Weizmann Institute of Science
15:30
HCMV DOWNREGULATES AN NKG2D LIGAND TO ESCAPE ELIMINATION BY NK CELLS
Einat Seidel, The Hebrew University of Jerusalem
15:45
THE HIPPO PATHWAY AND VIRAL ONCOGENESIS: TAZ AUGMENTS POLYOMAVIRUS
MIDDLE T-ANTIGEN ONCOGENICITY IN A LATS DEPENDENT MANNER
Matan Shanzer, Weizmann Institute of Science
16:00
NUCLEAR ACTIN FILAMENTS IN PLANT VIRUS INFECTION SITES
Amit Levy, Cornell University, NY, USA
16:15
A PHOSPHOINOSITIDE-BINDING DOMAIN COUPLES MEMBRANE LOCALIZATION AND
FOLDING OF BACTERIAL EFFECTORS IN HOST CELLS
Dor Salomon, University of Texas Southwestern Medical Center, TX, USA
29
Wednesday, February 12, 2014
15:00-16:30
Parallel Oral Poster Session OP15:
Immunological journey: homeostasis, pathology and therapy
Chairperson: Adit Ben-Baruch (Tel Aviv University)
Hall F - Dan
15:00
DENDRITIC CELLS CONTROL CNS AUTOIMMUNITY BY INDUCTION OF REGULATORY T
CELLS THROUGH PD-L/PD-1 INTERACTION
Nir Yogev, Gutenberg University of Mainz, Germany
15:15
THE DISCOVERY OF THE IMMUNE MODULATORY ROLE OF A CD2 IMMUNOGLOBULIN-LIKE
RECEPTOR THROUGH TUMOR-CD8 T CELL INTERACTIONS
Michal Lotem, Hadassah Hebrew University Hospital
15:30
RIPK1, A MASTER REGULATOR OF CELL DEATH AND INFLAMMATION
Mordechay Gerlic, Walter and Eliza Hall Institute of Medical Research and University of Melbourne,
Australia
15:45
THE ROLE OF CLARA CELL SENESCENCE IN THE PATHOGENIC MECHANISM OF COPD
Adi Sagiv, Weizmann Institute of Science
16:00
LINKING THE ENDOSOME TO PRIMARY IMMUNODEFICIENCY - A CONGENITAL
NEUTROPHIL SYNDROME ASSOCIATED WITH MUTATIONS IN VPS45
Amos J. Simon, Sheba Medical Center
16:15
HARNESSING NANOTECHNOLOGY FOR THERAPY OF INFLAMMATORY BOWEL DISEASE
Meirav Katz, Tel Aviv University
15:00-16:30
Parallel Oral Poster Session OP16:
Cell dynamics and signaling
Chairperson: Alexander D. Bershadsky (Weizmann Institute of Science)
Hall H - Royal Beach
15:00
TRANSPORT AND SIGNALING OF TRANSFORMING GROWTH FACTOR - β RECEPTORS:
REGULATION BY MOLECULAR MOTIFS, CELLULAR FACTORS AND THE CELL CYCLE
Marcelo Ehrlich, Tel Aviv University
15:15
THE ROLE OF INCLUSIONS, CYTOSKELETON, AND STRESS FOCI IN SPATIAL QUALITY
CONTROL OF PROTEIN FOLDING
Daniel Kaganovich, The Hebrew University of Jerusalem
15:30
Ypf1 MEDIATED DEGRADATION OF HIGH-AFFINITY TRANSPORTERS IS ESSENTIAL FOR
EARLY SENSING AND RESPONSE TO NUTRIENT DEPLETION
Shai Fuchs, Weizmann Institute of Science
15:45
SEQUESTRATION OF CDH1 BY MAD2L2 PREVENTS PREMATURE APC/C ACTIVATION
DURING THE METAPHASE TO ANAPHASE TRANSITION
Tamar Listovsky, MRC Laboratory of Molecular Biology, UK
16:00
THE ARGONAUTE CSR-1 CONTRIBUTES TO CHROMOSOME SEGREGATION IN C.
ELEGANS EMBRYOS VIA REGULATION OF THE MICROTUBULE DEPOLYMERASE MCAK
Adina Gerson-Gurwitz, Ludwig Institute for Cancer Research, CA, USA
16:15
POLY Q AGGREGATES DEPLETE NUCLEAR UBIQUITIN, LEAD TO HISTONE
DE-UBIQUITINATION AND IMPAIR THE DNA DAMAGE RESPONSE
Michael Brandeis, The Hebrew University of Jerusalem
30
Wednesday, February 12, 2014
15:00-16:30
Parallel Oral Poster Session OP17:
Cancer microenvironment
Chairperson: Sara Lavi (Tel Aviv University)
Hall I - Royal Beach
15:00
A CENTRAL ROLE FOR STROMAL HEAT SHOCK FACTOR 1 IN SUPPORTING MALIGNANCY
Ruth Scherz-Shouval, Whitehead Institute for Biomedical Research, MA, USA
15:15
CYTOSOLIC PPARGAMMA INTERACTS WITH THE LIPIDPHOSPHATASE MTMR7 TO REDUCE
SURVIVAL OF WNT/RAS-MUTATED HUMAN COLORECTAL CANCER CELLS VIA INHIBITION
OF PKB/AKT
Elke Burgermeister, Heidelberg University, Germany
15:30
MICRORNA TRAFFICKING VIA MELANOSOMES DRIVE MELANOMA AND NEIGHBORING
CELLS COMUNNICATION
Shani Dror, Tel Aviv University
15:45
THE ROLE OF TUMOR-DERIVED STROMAL CELLS IN MODULATING THE BEHAVIOR OF
CANCER CELLS
Liron Berger, Technion-Israel Institute of Technology
16:00
HEPARANASE2 EXPRESSION IS DECREASED IN HUMAN CANCER AND ATTENUATES
LYMPHANGIOGENESIS
Miriam Gross-Cohen, Technion-Israel Institute of Technology
16:15
MIR-675, THE PRODUCT OF H19 TARGETS THE APOPTOTIC GENE FADD AND MAY AFFECT
BOTH CELL DEATH AND PROLIFERATION
Rona Harari-Steinfeld, Hadassah Hebrew University Hospital
15:00-16:30
Parallel Oral Poster Session OP18:
Structure and function of large complexes - from viruses to human Hall J - Royal Beach
Chairperson: Nathan Nelson (Tel Aviv University)
15:00
STRUCTURES OF TWO PHAGE MIMETIC PSI COMPLEXES
Yuval Mazor, Tel Aviv University
15:15
CRYSTALLOGRAPHIC VISUALIZATION OF AN INITIAL STAGE OF PROTEIN DENATURATION
Noam Adir, Technion-Israel Institute of Technology
15:30
TOWARDS STRUCTURAL STUDIES ON RIBOSOMES OF A PATHOGENIC BACTERIA
Zohar Baram, Weizmann Institute of Science
15:45
PROTEIN KINASE A SIGNALING NETWORK: VISUALIZING THROUGH MACROMOLECULAR
ASSEMBLY AND HIGH RESOLUTION MOSAIC IMAGING OF THE BRAIN
Ronit Ilouz, University of California at San Diego, CA, USA
16:00
THE HUMAN CENTROMERIC CENP-A CHROMATIN PARTICLE IS AN OCTAMERIC
NUCLEOSOME ACROSS THE CELL CYCLE
Yael Nechemia-Arbely, University of California at San Diego, CA, USA
16:15
AN ESSENTIAL ROLE FOR UBIQUITIN IN TRIGGERING THE AGGREGATION OF PARTILLAYMISFOLDED PROTEINS
Ayala Shiber, The Hebrew University of Jerusalem
31
Wednesday, February 12, 2014
15:00-16:30
Parallel Oral Poster Session OP19:
Mechanisms regulating developmental pathways and behavior
Chairperson: Joel Yisraeli (The Hebrew University of Jerusalem)
Hall K - Herods Palace
15:00
GENOME-WIDE STUDY OF PARENTAL IMPRINTING IN HUMAN PARTHENOGENETIC IPS
CELLS
Yonatan Stelzer, The Hebrew University of Jerusalem
15:15
VEGF GENERATES A FULLY FUNCTIONAL NICHE FOR HEMATOPOIETIC STEM CELLS IN
THE SPLEEN
Myriam Grunewald, Hadassah Hebrew University Hospital
15:30
THE CHROMATIN REMODELER Mi-2β PROMOTES ERYTHROCYTE MATURATION BY
DICHOTOMOUS REGULATION OF ELONGATION AND REPRESSION OF Wnt/β CATENIN
Idit Hazan, Massachusetts General Hospital and Harvard Medical School, MA, USA and The Hebrew
University of Jerusalem
15:45
ISLET CELL TRANSDIFFERENTIATION IN A PHARMCOLOGICALLY INDUCED MODEL AND
TYPE I DIABETES
Ron Piran, Sanford-Burnham Medical Research Institute, CA, USA
16:00
RNA EDITING AND ZEBRAFISH AS A MODEL FOR MENTAL RETARDATION
Adi Shamay-Ramot, Bar-Ilan University
16:15
EDITED MICRORNA REGULATES DAILY LOCOMOTOR RHYTHMS IN ZEBRAFISH
Shahar Alon, Tel Aviv University
16:30-17:00
Coffee Break and Exhibition
17:00-19:30
PARALLEL SESSIONS: A5, B3, C2, D2, D6, E5, K3, G6, G3, F4, K4
17:00-19:30
Parallel Session A5:
From chromatin organization to RNA processing
Hall A - Herods Boutique
Chairpersons: Shulamit Michaeli (Bar-Ilan University) and Eran Segal (Weizmann Institute of Science)
17:00
CHROMATIN ORGANIZATION AND DNA METHYLATION REGULATE ALTERNATIVE SPLICING
Gil Ast, Tel Aviv University
17:25
THE SUPRASPLICEOSOME - A MASTER REGULATOR OF PRE-mRNA PROCESSING
Ruth Sperling, The Hebrew University of Jerusalem
17:50
THE SPLICED LEADER RNA OF TRYPANOSOMES DETERMINES THE LIFE AND DEATH OF
THE PARASITE
Shulamit Michaeli, Bar-Ilan University
18:15
UNRAVELING PRINCIPLES OF GENE REGULATION USING THOUSANDS OF DESIGNED
REGULATORY SEQUENCES
Eran Segal, Weizmann Institute of Science
18:40
E2F1-REGULATED LONG NON-CODING RNAS MODULATE CELL PROLIFERATION AND
VIABILITY
Doron Ginsberg, Bar-Ilan University
19:05
CONSERVED FUNCTIONS OF LONG NONCODING RNAs IN VERTEBRATE EMBRYONIC
DEVELOPMENT
Igor Ulitsky, Whitehead Institute, MA, USA and Weizmann Institute of Science
32
Wednesday, February 12, 2014
17:00-19:30
Parallel Session B3:
Signaling in disease and angiogenesis
Hall B - Herods Boutique
Chairpersons: Eli Keshet (The Hebrew University-Hadassah Medical School) and Karina Yaniv (Weizmann
Institute of Science)
17:00
VASCULAR NICHES OF ADULT STEM CELLS
Eli Keshet, The Hebrew University-Hadassah Medical School
17:25
ELUCIDATING THE ROLE OF LIPOPROTEINS IN TUMOR-RELATED ANGIOGENESIS AND
METASTASIS
Karina Yaniv, Weizmann Institute of Science
17:50
CHANGES IN THE EXPRESSION LEVELS OF PLEXINS ENABLE CELLS TO DIFFERENTIATE
BETWEEN CLASS-3 SEMAPHORINS AND DETERMINE HOW MIGRATING CELLS RESPOND
TO INTERSECTING GRADIENTS OF SEMAPHORINS
Gera Neufeld, Technion-Israel Institute of Technology
18:15
PHOSPHOINOSITIDE SIGNALING IN BREAST CANCER MIGRATION AND METASTASIS
Sima Lev, Weizmann Institute of Science
18:40
ENDOTHELIAL CELLS REGULATE NEURAL CREST AND SECOND HEART FIELD
DEVELOPMENT VIA TRANSFORMING GROWTH FACTOR BETA 1-MEDIATED ECM
REMODELING
Eldad Tzahor, Weizmann Institute of Science
19:05
TUMOR INDUCED MOBILIZATION OF LY6G+ NEUTROPHILS FACILITATES METASTASIS
THROUGH ACTIVATION OF ENDOTHELIAL CELLS AND PROTEASE MEDIATED
EXTRAVASATION
Asaf Spiegel, Whitehead Institute for Biomedical Research, MA, USA
17:00-19:30
Parallel Session C2:
Plant responses and signaling to abiotic stress
Hall C - Herods Boutique
Chairpersons: Simon Barak (Ben-Gurion University of the Negev) and Hillel Fromm (Tel Aviv University)
17:00
AN ABA-ACTIVATED MAP KINASE CASCADE REGULATES DROUGHT TOLERANCE IN
ARABIDOPSIS
Heribert Hirt, Saclay Plant Sciences, France
17:25
SERPIN CONTROL OF CELL-DEATH PROTEASES DURING BIOTIC AND ABIOTIC STRESS
Robert Fluhr, Weizmann Institute of Science
17:50
CYTOSOLIC ASCORBATE PEROXIDASES: THE GATEKEEPERS OF THE ROS-SIGNALING
HUB IN ARABIDOPSIS THALIANA
Gad Miller, Bar-Ilan University
18:15
A CROSS-SPECIES META-ANALYSIS REVEALS KEY PATHWAYS IN PLANT ADAPTATION TO
DROUGHT STRESS
Zvi Peleg, The Hebrew University of Jerusalem
18:40
PROTEIN TURNOVER IN ABIOTIC STRESS AND ROOT SIGNALING
Dudy Bar-Zvi, Ben-Gurion University of the Negev
19:05
CALCIUM-REGULATED TRANSCRIPTIONAL SWITCHES OF DEFENSE RESPONSES
Hillel Fromm, Tel Aviv University
33
Wednesday, February 12, 2014
17:00-19:30
Parallel Session D2:
Microbes in the environment
Hall D - Dan
Chairpersons: Edward A. Bayer (Weizmann Institute of Science) and Oded Béjà (Technion-Israel Institute of
Technology)
17:00
MODULATION OF TRANSCRIPT STABILITY IN RESPONSE TO ENVIRONMENTAL STRESS
Eliora Z. Ron, MIGAL-Galilee Research Institute and Tel Aviv University
17:25
INSIGHTS INTO THE BOVINE RUMEN MICROBIOME
Itzhak Mizrahi, Volcani Research Center
17:50
DIVERSE LIGNOCELLULOSE ECOSYSTEMS BREED A STRANGE COLLECTION OF
MICROBIAL BEDFELLOWS
Edward A. Bayer, Weizmann Institute of Science
18:15
PROGRAMMED CELL DEATH IN THE MARINE CYANOBACTERIUM TRICHODESMIUM SPP.
MEDIATES OCEANIC CARBON AND NITROGEN FLUXES
Ilana Berman-Frank, Bar-Ilan University
18:40
METAGENOME AND METATRANSCRIPTOME ANALYSIS OF PLANT ROOT ASSOCIATED
BACTERIAL COMMUNITIES
Dror Minz, Volcani Research Center
19:05
VIRAL-INSPIRED PHOTOSYNTHESIS?
Oded Béjà, Technion-Israel Institute of Technology
17:00-19:30
Parallel Session D6:
Immune regulation and development
Hall E - Dan
Chairpersons: Zvi Fishelson (Tel Aviv University) and Nir Friedman (Weizmann Institute of Science)
17:00
mTOR ACTIVATION PROMOTES PLASMA CELL DIFFERENTIATION AND BYPASSES THE
UPR FOR IMMUNOGLOBULIN SECRETION
Boaz Tirosh, The Hebrew University of Jerusalem
17:25
REGULATION OF CELL DEATH BY THE MITOCHONDRIAL HEAT SHOCK PROTEIN
MORTALIN/GRP75
Zvi Fishelson, Tel Aviv University
17:50
NEW GENETIC ADJUVANTS FOR AUTONOMOUS REGULATION OF T CELL FUNCTION IN
ADOPTIVE CELL THERAPY OF CANCER
Gideon Gross, MIGAL-Galilee Research Institute and Tel-Hai College
18:15
NEW PERSPECTIVES ON T CELL RECEPTOR REPERTOIRES REVEALED BY HIGHTHROUGHPUT SEQUENCING: SELF ASSOCIATED T CELLS GO PUBLIC
Nir Friedman, Weizmann Institute of Science
18:40
BRAIN-REGULATED IMMUNITY
Asya Rolls, Technion-Israel Institute of Technology
19:05
IN VIVO IMAGING REVEALS THE BONE MARROW AS A DEPOT FOR MATURE
PROLIFERATING NK CELLS
Guy Shakhar, Weizmann Institute of Science
34
Wednesday, February 12, 2014
17:00-19:30
Parallel Session E5:
Molecular, cellular and neuronal network basis of pain
Hall F - Dan
Chairpersons: Alexander Binshtok (The Hebrew University of Jerusalem) and Marshall Devor (The Hebrew
University of Jerusalem)
17:00
WHEN THE MACHINE IS ON FIRE: PERIPHERAL MECHANISMS OF INFLAMMATORY PAIN
Alexander Binshtok, The Hebrew University of Jerusalem
17:25
WHEN THE MACHINE BREAKS DOWN: MECHANISM OF PAIN IN PHANTOM LIMBS AND
OTHER NEUROPATHIES
Marshall Devor, The Hebrew University of Jerusalem
17:50
TARGETING THE PROMISCUOUS VOLTAGE SENSOR OF KV7.2 AND TRPV1 CHANNELS
WITH NEW GATING-MODIFIERS TO CURE HYPEREXCITABILITY DISORDERS
Bernard Attali, Tel Aviv University
18:15
GENOTYPE-SELECTIVE PHENOTYPIC SWITCH IN PRIMARY AFFERENT NEURONS
CONTRIBUTES TO NEUROPATHIC PAIN
Michael Tal, The Hebrew University of Jerusalem
18:40
THE ROLE OF SATELLITE GLIAL CELLS IN LOCALIZED AND SYSTEMIC PAIN
Menachem Hanani, Hadassah Hebrew University Hospital
19:05
General discussion
17:00-19:30
Parallel Session K3:
Postdoctoral academia meeting (by invitation)
Chairperson: Yinon Ben-Neriah (The Hebrew University of Jerusalem)
Hall G - Dan
OPENING REMARKS
Ruth Arnon, President of the Israel Academy of Sciences
POSTDOCTORAL FELLOW PRESENTATION
Shulamit Katzav-Shapira, The Hebrew University of Jerusalem
ROUND TABLE DISCUSSION WITH LEADING ISRAELI SCIENTISTS FROM ACADEMIA
AND MEDICAL INSTITUTIONS
Karen B. Avraham, Tel Aviv University
17:00-19:30
Parallel Session G6:
Regenerative medicine
Hall H - Royal Beach
Chairpersons: Yossi Buganim (The Hebrew University of Jerusalem) and Eithan Galun (Hadassah Hebrew
University Hospital)
17:00
GENERATION OF SERTOLI-LIKE CELLS FOR INFERTILITY TREATMENT AND
NEURODEGENERATIVE DISEASES
Yossi Buganim, The Hebrew University of Jerusalem
17:25
AN INNOVATIVE ENDOSCOPIC PROCEDURE FOR CURING TYPE 2 DIABETES
Yoav Mintz, Hadassah Hebrew University Hospital
17:50
CELL THERAPY FOR PARKINSON'S DISEASE BY EMBRYONIC STEM CELL-DERIVED
NEURONS- SOLUTIONS FOR PRESSING ISSUES
Sharona Even-Ram, Hadassah Hebrew University Hospital
18:15
HUMAN EMBRYONIC LUNG TISSUE AS A NEW SOURCE FOR LUNG REPAIR
Yair Reisner, Weizmann Institute of Science
18:40
SALIVARY GLANDS STEM CELL AND REGENERATION
Aaron Palmon, The Hebrew University of Jerusalem
19:05
DRIVING IN VIVO HEART PROGENITOR CELL FATE AND VASCULAR REGENERATION VIA
MODIFIED MRNA
Lior Zangi, Harvard University and Massachusetts General Hospital, MA, USA
35
Wednesday, February 12, 2014
17:00-19:30
Parallel Session G3:
Cancer systems biology
Hall I - Royal Beach
Chairpersons: Ron Shamir (Tel Aviv University) and Yosef Yarden (Weizmann Institute of Science)
17:00
CHROMOSOME ORGANIZATION AND GENE FUNCTION IN NORMAL AND TUMOR CELLS
Ron Shamir, Tel Aviv University
17:25
CANCER RNA EPIGENETICS
Gideon Rechavi, Sheba Medical Center and Tel Aviv University
17:50
GENE EXPRESSION PROGRAMS STIMULATED BY GROWTH FACTORS AND RECEPTOR
TYROSINE KINASES: WHAT DO THEY TELL US ABOUT TUMOR PROGRESSION?
Yosef Yarden, Weizmann Institute of Science
18:15
GENOME-WIDE DETECTION OF SYNTHETICALLY-LETHAL GENES UNCOVERS SELECTIVE
CANCER DRUG TARGETS
Eytan Ruppin, Tel Aviv University
18:40
WHAT DO WE KNOW ABOUT THE NORMAL PROGENITOR OF BREAST CARCINOMA?
Izhak Haviv, Peter MacCallum Cancer Center, University of Melbourne, Australia and Bar-Ilan
University
19:05
ADDICTION OF t(8;21) AND inv(16) ACUTE MYELOID LEUKEMIA TO NATIVE RUNX1
Yoram Groner, Weizmann Institute of Science
17:00-19:30
Parallel Session F4:
Neural cell migration and patterning
Hall J - Royal Beach
Chairpersons: Adi Inbal (The Hebrew University of Jerusalem) and Orly Reiner (Weizmann Institute of
Science)
17:00
NEW ROLES FOR TRANSCRIPTION FACTOR SIX3 IN BRAIN AND EYE DEVELOPMENT
Adi Inbal, The Hebrew University of Jerusalem
17:25
USING THE ZEBRAFISH MODEL TO STUDY THE DEVELOPMENT AND FUNCTION OF THE
HYPOTHALAMUS
Gil Levkowitz, Weizmann Institute of Science
17:50
A NEW NICHE OF NEURAL PROGENITORS/STEM CELLS AT EMBRYONIC HINDBRAIN
BOUNDARIES
Dalit Sela-Donenfeld, The Hebrew University of Jerusalem
18:15
UNORTHODOX ACTIVITIES OF COMPONENTS OF THE COMPLEMENT PATHWAY IN
REGULATION OF RADIAL NEURONAL MIGRATION
Orly Reiner, Weizmann Institute of Science
18:40
STEPWISE PROSPECTIVE ISOLATION OF DISTINCT HUMAN ES CELL DERIVED NEURAL
STEM CELL TYPES ENABLES DIRECTED MODELING OF CORTICAL DEVLOPMENT
Yechiel Elkabetz, Tel Aviv University
19:05
MFSD2A IS CRITICAL FOR THE FORMATION AND FUNCTION OF THE BLOOD BRAIN
BARRIER
Ayal Ben-Zvi, Harvard Medical School, MA, USA
36
Wednesday, February 12, 2014
17:00-19:30
Parallel Session K4:
Threats on life and health sciences research in Israel (IN HEBREW)
Hall K - Herods Palace
Chairpersons: Yechezkel Barenholz (The Hebrew University of Jerusalem) and Alexander Tsafriri
(Weizmann Institute of Science)
17:00
Opening
17:20
EVALUATION OF PROPOSED METHODS AS POTENTIAL REPLACEMENT METHODS TO STUDY
HUMAN PATHOLOGY
Hillel Bercovier, Chairman of The National Council for Animal Experimentation and The Hebrew
University of Jerusalem
17:40
PRE-CLINICAL IMAGING - A WAY TO MINIMIZE ANIMAL USAGE WITHOUT COMPROMISING
RESEARCH QUALITY
Rinat Abramovitch, Hadassah Hebrew University Hospital
17:50
FUTURE OF ANIMAL EXPERTIMENTATION AND THE POSSIBLE CONSEQUENCES OF ANIMAL
EXPERIMENTATION ABOLISHMENT
Roey Tzezana, Tel Aviv University
18:10
THE ‘T-BODY’ (CAR) APPROACH: FROM THE MOUSE CAGE TO THE PATIENT’S BED
Zelig Eshhar, Tel Aviv Souraski Medical Center and Weizmann Institute of Science
18:30
EXPLOITING BASAL GANGLIA PHYSIOLOGY FOR THE CURE OF BASAL GANGLIA DISORDERS
Hagai Bergman, The Hebrew University of Jerusalem
18:50
LESSONS FROM THE DEVELOPMENT OF DOXIL THE 1 FDA APPROVED NANO-DRUG: ANIMAL
STUDIES ARE OBLIGATORY FOR NANO-DRUG DEVELOPMENT
Yechezkel Barenholz, The Hebrew University-Hadassah Medical School
19:10
Round table discussion
ST
Discussants:
Above speakers and
John Finberg, Technion-Israel Institute of Technology
Alexander Tsafriri, Weizmann Institute of Science
Ehud Ziv, previous Chairman of The National Council for Animal Experimentation and The
Hebrew University of Jerusalem
19:30-21:30
Poster Session B and Buffet Dinner
37
Isrotel Sport Club
Thursday, February 13, 2014
08:00-09:00
Plenary 5
Chairperson: Eithan Galun (Hadassah Hebrew University Hospital)
08:00
LIVER INFLAMMATION AND CANCER
Michael Karin, University of California at San Diego, California, USA
09:00-09:30
Coffee Break and Exhibition
09:30-10:30
Plenary 6
Chairperson: Rony Seger (Weizmann Institute of Science)
09:30
Hall A - Herods Boutique
Hall A - Herods Boutique
HIGHER-ORDER ASSEMBLIES IN SIGNAL TRANSDUCTION OF THE IMMUNE SYSTEM
Hao Wu, Boston Children's Hospital and Harvard Medical School, MA, USA
10:30-11:00
Katzir Prize Ceremony
Chairperson: Eithan Galun, Katzir Prize Committee
Hall A - Herods Boutique
Prize Ceremony: Haim Garty, Vice-President, Weizmann Institute of Science
ILANIT-Katzir Prize Awardee
Israel Silman, Weizmann Institute of Science
ILANIT-Katzir Prize Awardee
Joel Sussman, Weizmann Institute of Science
11:00-11:15
CLOSING CEREMONY
Chairperson: Yinon Ben-Neriah, Congress President
Hall A - Herods Boutique
Closing Remarks:
Karen B. Avraham, Congress Deputy-President
Yinon Ben-Neriah, Congress President
38

Scientific Program

Arrive at Midreshet Ben Gurion 8:00 WOL 2014

The parturient with cardiac disease

Nanoscale Assembly and Transport in Biosystems