SECOND JOINT MEETING ON BREAST CANCER UNIVERSITY OF INSUBRIA – MEMORIAL SLOAN KETTERING CANCER CENTER May, 21st – 22nd 2015 Regina Palace Hotel, Stresa (VB) COURSE DESCRIPTION The course provides a multidisciplinary review and update on the diagnosis and management of patients with breast carcinoma. The presentations will focus on recent diagnostic and therapeutic advances, and emphasize their practical implications. Some of the lectures will include discussion of the results of experimental studies to highlight recent progress in the understanding of breast carcinoma and future directions for its treatment. The course faculty consists of a cadre of experts in the diagnosis and treatment of breast carcinoma from Italy, European Cancer Centers and from Memorial SloanKettering Cancer Center, United States of America. Target Audience The course is intended for physicians and nursing staff involved in the care of patients with breast carcinoma and wish to broaden their knowledge of the disease. Educational Objective Upon completing this course, participants will: - understand benefits and limitations of the latest techniques for the radiologic detection of breast carcinoma; - understand the principles underlying classification and staging of breast carcinoma and their implications for patient care; - understand the benefits and limitations of sentinel lymph node biopsy in the management of patients with breast carcinoma; - familiarize themselves with the latest concepts and options for diagnosis and treatment of patients with breast carcinoma; - understand the clinical relevance of recent advances in the basic research of breast cancer. Day 1, May 21st, 2015 7.30 – 8.00 Registration 8.00 – 8.10 Welcome and Introduction - Renzo Dionigi – Emeritus Professor of General Surgery, University of Insubria, Varese - Gianlorenzo Dionigi - Associate Professor of Surgery, Director 1st Division of Surgery University of Insubria, Varese - Eugenio Cocozza - Director of General Surgery Department Azienda Ospedaliera Ospedale di Circolo Fondazione Macchi Varese - Francesca Rovera – Course Director, Associate Professor of General Surgery, Director of the Senology Research Center, University of Insubria SESSION I – Radiologic Assessment Moderators: Elisabeth Morris - Memorial Sloan Kettering Cancer Center, New York Roberto Murgo - San Giovanni Rotondo, Bari Franca Sambo - ASL Varese 8.10 – 8.40 Lecture (To be defined) 8.40 – 8.55 Screening in Italy Alfonso Frigerio – Mammography Screening, Turin 8.55 – 9.20 Breast ultrasound, when and how? Adriana Bonifacino – Sant’Andrea Hospital, Rome 9.20 – 9.45 Magnetic resonance: a new era in breast cancer screening Elisabeth Morris - Memorial Sloan Kettering Cancer Center, New York 9.45 – 10.10 Magnetic resonance: a new era in clinical practice Francesco Sardanelli – Policlinico San Donato, University of Milan School of Medicine, Milan 10.10 – 10.35 Tomosynthesis: where we are and where do we go Pietro Panizza – National Cancer Institute, Milan 10.35 – 10.45 Questions Radiologic Assessment 10.45 – 11.00 Coffee Break SESSION II – Surgical Advances Moderators: Francesco Caruso – Humanitas Catania Alberto Costa – Ente Ospedaliero Cantonale, Bellinzona Monica Morrow – Memorial Sloan Kettering Cancer Center, New York 11.00 – 11.30 Margins in conserving surgery: a clinical perspective Monica Morrow – Memorial Sloan Kettering Cancer Center, New York 11.30 – 11.55 When can we spare sentinel lymph node biopsy and axillary dissection? Oreste Gentilini - European Institute of Oncology, Milan 11.55 – 12.20 New methods for sentinel lymph node identification Bettina Ballardini - European Institute of Oncology, Milan 12.20 – 12.30 Questions Surgical Advances 12.30 – 13.30 Round table with questionnaire and discussion: surgical advances, chemotherapy, hormonal therapy, immunotherapy, radiotherapy Corrado Chiappa – University of Insubria, Varese Radiology: E. Morris, P. Panizza Surgery: R. Audisio, M. Morrow, F. Rovera, V. Sacchini, C. Tinterri Plastic Surgery: M. Nava, L. Valdatta Pathology: F. Sessa, L. Tan Oncology: F. Peccatori, G. Giardina Physiotherapy: AM. Grande Radiotherapy: P. Antognoni, A. Richetti 13.30 – 14.30 Lunch SESSION III – Special Conditions Moderators: Riccardo Audisio – University of Liverpool Claudio Andreoli - Istituto Clinico Humanitas Rozzano, Milan Adriana Bonifacino – Sant’Andrea Hospital, Rome 14.30 – 14.50 Breast surgery in young women Mario Taffurelli – Policlinico Sant’Orsola Malpighi, Bologna 14.50 – 16.10 Breast cancer and pregnancy Francesca Rovera – University of Insubria, Varese Sibylle Loibl - Offenbach (Germany) Fedro Peccatori – European Institute of Oncology, Milan Fabio Ghezzi – University of Insubria, Varese 16.10 – 16.20 Questions Special Conditions 16.20 – 16.40 Coffee Break SESSION IV – New Technologies Moderators: Oreste Gentilini - European Institute of Oncology, Milan Virgilio Sacchini - Memorial Sloan Kettering Cancer Center, New York Luigi Valdatta – University of Insubria, Varese 16.40 – 17.40 Nipple sparing mastectomy, when and how? Maurizio Nava – National Cancer Institute, Milan Virgilio Sacchini - Memorial Sloan Kettering Cancer Center, New York 17.40 – 18.10 Surgery in the elderly Riccardo Audisio – University of Liverpool 18.10 – 18.30 Secondary lymphedema of the upper limbs: state of the art Sylvain Mukenge – San Raffaele Hospital, Milan 18.30 – 18.40 Questions New Technologies 18.40 Closing first day Day 2, May 22nd, 2015 8.30 – 8.40 Introduction - Francesca Rovera – Course Director, Associate Professor of General Surgery, Director of the Senology Research Center, University of Insubria SESSION V – Pathologic Assessment Moderators: Sibylle Loibl - Offenbach (Germany) Giuliano Lucani – Policlinico di Monza Fausto Sessa – University of Insubria Varese 8.40 – 9.10 Classification of breast cancer: from morphology to molecular phenotypes Giuseppe Viale – European Institute of Oncology, Milan 9.10 – 9.30 Androgen receptors and breast cancer Cristina Riva – University of Insubria, Varese 9.30 – 09.50 Pathologic assessment after neoadjuvant therapy Adriana Dionigi Corben - Memorial Sloan Kettering Cancer Center, New York 09.50 – 10.20 “Small cell” tumors of the breast Lee Tan - Memorial Sloan Kettering Cancer Center, New York 10.20 – 10.30 Questions Pathologic Assessment 10.30 – 11.00 Coffee Break 11.00 – 11.30 The breast in the art Renzo Dionigi – Emeritus Professor of General Surgery University of Insubria 11.30 – 12.30 Round Table with questionnaire and discussion: high risk patients, chemotherapy, hormonal therapy, immunotherapy, radiotherapy Corrado Chiappa, Anna Fachinetti – University of Insubria, Varese Radiology: A. Bonifacino, F. Sardanelli Surgery: R. Audisio, M. Grassi, M. Morrow, V. Sacchini Plastic Surgery: L. Valdatta Pathology: F. Sessa, G. Viale, L. Tan Oncology: G. Giardina, A. Goldhirsch, S. Loibl, F. Peccatori Genetics: B. Bonanni, MG. Tibiletti 12.30 – 13.30 Lunch SESSION VI – Update in Oncologic Treatment Moderators: Graziella Pinotti – Oncology Unit Varese Fedro Peccatori - European Institute of Oncology, Milan 13.30 – 14.00 Genetic profile for treatment Aaron Goldhirsch - European Institute of Oncology, Milan 14.00 – 14.30 Hereditary breast cancer, management of BRCA positive patients Bernardo Bonanni – European Institute of Oncology, Milan 14.30 – 15.00 Guidelines for young cancer patients Olivia Pagani – Ente Ospedaliero Cantonale, Bellinzona 15.00 – 15.30 New approaches to individual radiotherapy in breast cancer Antonella Richetti – Ente Ospedaliero Cantonale, Bellinzona 15.30 – 16.00 New technologies in breast surgery Virgilio Sacchini - Memorial Sloan Kettering Cancer Center, New York 16.00 – 16.30 Electrochemotherapy for skin metastases from breast cancer Maria Renne – Fondazione “Tommaso Campanella”, Catanzaro 16.30 – 17.00 Breast unit: where are we now? Corrado Tinterri – Istituto Clinico Humanitas Rozzano, Milan 17.00 – 17.10 Questions 17.10 – 17.30 The role of the voluntary associations Adele Patrini – C.A.O.S., Varese 17.30 – 17.45 Concluding remarks and take-home messages Virgilio Sacchini - Memorial Sloan Kettering Cancer Center, New York Francesca Rovera – University of Insubria Varese Adriana Dionigi Corben - Memorial Sloan Kettering Cancer Center, New York 18.00 Aperitif Claudio Andreoli - Rozzano, Milan (Italy) Paolo Antognoni - Varese (Italy) Riccardo Audisio – Liverpool (UK) Bettina Ballardini - Milan (Italy) Bernardo Bonanni – Milan (Italy) Adriana Bonifacino – Rome (Italy) Francesco Caruso – Catania (Italy) Corrado Chiappa – Varese (Italy) Eugenio Cocozza – Varese (Italy) Alberto Costa – Bellinzona (Switzerland) Adriana Dionigi Corben – New York (USA) Gianlorenzo Dionigi - Varese (Italy) Renzo Dionigi – Varese (Italy) Anna Fachinetti – Varese (Italy) Alberta Ferrari – Pavia (Italy) Alfonso Frigerio – Turin (Italy) Oreste Gentilini – Milan (Italy) Fabio Ghezzi – Varese (Italy) Giovanni Giardina – Varese (Italy) Aaron Goldhirsch – Milan (Italy) Anna Maria Grande – Varese (Italy) Massimo Grassi – Bergamo (Italy) Sibylle Loibl - Offenbach (Germany) Giuliano Lucani – Monza (Italy) Elisabeth Morris – New York (USA) Monica Morrow – New York (USA) Sylvain Mukenge – Milan (Italy) Roberto Murgo – San Giovanni Rotondo, Bari (Italy) Maurizio Nava – Milan (Italy) Olivia Pagani – Bellinzona (Switzerland) Pietro Panizza – Milan (Italy) Adele Patrini – Varese (Italy) Fedro Peccatori – Milan (Italy) Graziella Pinotti – Varese (Italy) Maria Renne – Catanzaro (Italy) Antonella Richetti – Bellinzona (Switzerland) Cristina Riva – Varese (Italy) Francesca Rovera – Varese (Italy) Virgilio Sacchini - New York (USA) Franca Sambo – Varese (Italy) Francesco Sardanelli – San Donato Milanese, Milan (Italy) Fausto Sessa – Varese (Italy) Mario Taffurelli – Bologna (Italy) Lee Tan – New York (USA) Maria Grazia Tibiletti - Varese (Italy) Corrado Tinterri –Rozzano, Milan (Italy) Luigi Valdatta – Varese (Italy) Giuseppe Viale – Milan (Italy)