Appendix 1 Case Sex Age Vaspin (ng/ml) Vaspin(ng/ml) (before) (After) Treatment 1 M 28 481.1 628.7 PSL30mg, TAC 6mg 2 F 56 87.2 106.6 PSL 5mg, TAC 5mg 3 F 40 182.7 878.7 PSL 20mg, AZA 50mg, LCAP 4 M 66 201.7 653.1 AZA 25mg, TAC 8mg 5 M 48 3.2 519.0 PSL 30mg, AZA 50mg, 6 M 41 1062.5 1344.1 AZA 75mg, CyA 120mg 7 M 44 398.8 835 PSL50mg 8 F 46 55.2 70.5 AZA50mg, IFX 5mg/Kg 9 F 61 61.4 439.1 PSL 2.5mg, CyA 150mg 10 F 51 376.8 567.3 AZA75mg, TAC 6mg 11 F 46 486 941.3 AZA50mg, TAC 6mg PSL: prednisolone TAC: tacrolimus AZA: azathioprine CyA: cyclosporin A IFX: infliximab LCAP: leukocytapheresis Appendix 2 P = N.S (pg/mL) P = N.S (pg/mL) P = N.S 1400 1200 1000 800 600 400 200 0 0.0 1.0 2.0 3.0 Proctitis Left-sided Extensive n=8 n = 14 n = 11 P = N.S 1600 Serum Vaspin Concentration Serum Vaspin Concentration 1600 P = N.S 4.0 P = N.S 1400 1200 1000 800 600 400 200 0 0.0 0.5 1.0 1.5 2.0 Chronic relapsingcontinuous remitting n=2 n = 28 2.5 Singleattack 3.0 3.5 n=3 * Kruskal-Wallis test
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